Acticin
Acticin

9.78
Acticin is a topical cream applied as a single treatment to eradicate scabies mite infestations on the skin.


Ingredient
Availability
In Stock
Delivery
Airmail (14-21 days) | EMS trackable (5-9 days)
Product is shipped in a fully discreet envelope with no content disclosure, including all required documentation inside

Product Sheet

Active Ingredient(s)
Permethrin
Reference Brand
Permethrin Topical Cream
Product Origin
Generic Alternative
Reference Manufacturer
Perrigo
Product Form
Cream
Regulatory Classification
Rx
Primary Category
Antiparasitics, Skin Care
Product Category
Scabicidal agents
Pharmacological Class
Pyrethroids
Clinical Indications
Scabies
Manufacturer Description
Acticin is a topical cream applied as a single treatment to eradicate scabies mite infestations on the skin.
Mechanism of Action
Permethrin interferes with the nerve cell ion transport of parasites, resulting in neurological paralysis and mite death.
Route of Administration
Topical
Onset Time
Immediate
Duration
Residual effects last for several days
Contraindications
Hypersensitivity to pyrethrin
Severe Adverse Events
Severe skin hypersensitivity
Common Side Effects
Mild burning sensation, Itching
Uncommon Side Effects
Irritation at application site
Pregnancy Safety Warnings
Consult provider if pregnant.
Age Restrictions
Consult a professional for use in children.
Storage Guidelines
Keep at room temperature.
Related Products
Lindane, Benzyl benzoate

Acticin FAQ

How does this bioequivalent alternative compare to the originator?

Generic Acticin uses the same Permethrin API and follows manufacturing standards that ensure comparable pharmacokinetic performance to the originator product.

Why do multi-source formulations vary in cost?

The pricing of branded generics accounts for different logistical paths and manufacturing overheads, rather than differences in the core efficacy of the Permethrin molecule.

How does this affiliate network coordinate logistics?

We facilitate connections to international, WHO-GMP compliant pharmacies solely for patients who have already obtained a clinical assessment and prescription from their primary physician.

Are there differences in formulation between brands?

While the API remains standardized, the inactive excipients and cream bases may vary, which can influence local skin texture and absorption rates without altering the primary mechanism.

How does storage affect formulation stability?

Exposure to extremes in temperature or light can destabilize the topical base, potentially reducing the uniformity of the Permethrin concentration upon application.

What are the import rules for Hong Kong residents?

Individuals must comply with local PPB regulations regarding the importation of pharmaceutical products, which may include personal use limits and the requirement for clinical documentation.

Does this product appear on standard drug tests?

Permethrin remains a localized antiparasitic agent, and there is no standard screening process that detects this compound in routine blood or urine testing.

Pharmacological Profile of Generic Acticin

Generic Acticin incorporates Permethrin as the primary active pharmaceutical ingredient within a topical cream formulation. This bioequivalent alternative provides a standardized 5% concentration, presented in 30g units commonly utilized for dermatological applications.

Acting via the pyrethroid class, the molecule targets the nervous systems of targeted ectoparasites. It functions specifically by disrupting sodium channel conductance across neuronal membranes. This interference triggers excessive neuronal excitation, leading to paralysis and subsequent termination of the organism.

Mechanisms of Biological Action

Permethrin coordinates its effects by binding directly to the voltage-gated sodium channels located on the nerve cell membranes of infesting parasites. This binding prolongs the opening of these channels, which facilitates an influx of sodium ions into the nerve cell. The resulting depolarization remains persistent, causing repetitive firing of nerve impulses. The organism loses motor coordination and respiratory function due to this central nervous system overstimulation.

Regulatory Scope and Clinical Application

The PPB classifies Permethrin as an antiparasitic agent indicated for the eradication of Sarcoptes scabiei infestations. It serves as a topical therapeutic analog for the treatment of scabies. Regulatory oversight by the PPB confirms its use exclusively for professional-led treatment protocols. This compound does not function as a preventative measure and possesses only localized, targeted activity upon contact.

Pregnancy and Developmental Risks

Consult a licensed healthcare provider in Hong Kong regarding use during pregnancy or lactation. Current data requires a formal risk-benefit evaluation by a physician before initiating treatment. The potential for systemic absorption during application necessitates professional clinical supervision.

Contraindications

Patients with a history of hypersensitivity reactions to synthetic pyrethroids or pyrethrins must avoid this product. Clinical documentation confirms that the compound may trigger cross-reactivity in individuals with allergies to chrysanthemum components.

Common Adverse Events

Localized cutaneous reactions represent the most frequently observed events. These include pruritus, transient burning, stinging sensations, and mild erythema at the site of application.

Serious Adverse Events

Systemic manifestations remain exceedingly rare with topical administration. Signs of significant skin irritation, such as persistent edema or contact dermatitis, indicate a need for immediate review by a healthcare professional.

Interactions

Drug interactions involving topical Permethrin are clinically minimal due to limited percutaneous absorption. Avoid concurrent application of other topical agents on the same site to prevent alterations in drug concentration or skin penetration characteristics.

Method of Administration

Apply the cream topically to the skin surface as directed by a healthcare professional. Ensure the cream touches all affected areas thoroughly. Total duration and frequency measurements reside solely within the purview of the prescribing physician.

Storage Requirements

Maintain the product at controlled room temperature, typically between 20°C and 25°C. Keep the container tightly closed after each use to prevent formulation degradation. Dispose of expired product through designated pharmaceutical waste programs to prevent environmental contamination.

Medical and Access Disclaimer

This content provides information only and does not replace medical advice, diagnosis, or treatment. Always consult a licensed healthcare provider in Hong Kong before altering any therapy. This service coordinates international logistical routing through regulated, WHO-GMP compliant pharmacies for users with prior physician authorization. We recommend checking local subsidized options under the Hong Kong national health framework first. This affiliate network acts strictly as a secondary resource. Licensed professionals in regulated jurisdictions perform all dispensing and medical reviews to support the continuity of care established by your doctor.

Glossary

Sodium Channel
Ion-conducting protein pores in cell membranes that facilitate the movement of sodium ions and allow for electrical signaling in nerve cells.
Pyrethroid
Synthetic chemical compounds that mimic the insecticidal activity of natural pyrethrins by interfering with the nervous systems of invertebrates.
Percutaneous Absorption
The transit of a substance from the outer environment through the layers of the skin into the systemic circulation.
Ectoparasite
An organism that lives on the exterior surface of a host, such as the skin, rather than within the body.
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