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Diabetes Management
Oral medicines for type 2 diabetes: metformin, sulfonylureas, pioglitazone, gliptins, gliflozins and semaglutide tablets, plus two-in-one combination tablets, as generic and branded listings.
Metformin, Pioglitazone
500/15mg
Actoplus Met pairs metformin with pioglitazone in one 500/15mg tablet for type 2 diabetes, sold as generic packs of 30 to 180 tablets.
Metformin
500/850/1000mg
Glucophage is metformin, a biguanide tablet for type 2 diabetes, sold in 500mg, 850mg and 1000mg strengths and in packs of 30 to 360 tablets.
Metformin
500mg
Generic Glucophage SR is a slow-release metformin tablet for type 2 diabetes, sold as 500mg tablets that are swallowed whole, usually once a day with the evening meal.
Metformin
1000mg
Glucophage Xr is a 1000mg slow-release metformin tablet for type 2 diabetes, taken once a day with the evening meal and sold in packs sized for long-term use.
Metformin, Glyburide
400/2.50/500/5mg
Glucovance tablets pair metformin with glyburide for type 2 diabetes, available in 400/2.50mg and 500/5mg strengths in packs of 30 to 360 tablets.
Saxagliptin, Metformin
5/500/5/1000mg
Generic Kombiglyze XR is a saxagliptin and metformin extended-release tablet for type 2 diabetes, sold as 5mg/500mg and 5mg/1000mg tablets taken once a day with the evening meal.
Glyburide, Metformin
2.5/400/5/500mg
Metformin + Glyburide combines two oral diabetes medicines in one tablet for type 2 diabetes, sold in 2.5/400mg and 5/500mg strengths.
Sitagliptin
50/100mg
Sitagliptin tablets in 50mg and 100mg strengths, packs of 10 to 90, a once-daily DPP-4 inhibitor that lowers blood sugar in adults with type 2 diabetes.
Most type 2 diabetes treatment begins with metformin, which cuts the amount of sugar the liver releases and makes the body respond better to its own insulin. The standard tablet is listed as Metformin and Glucophage in 500mg, 850mg and 1000mg, and as Glycomet in 500mg. Slower-release versions, Glucophage SR (500mg) and Glucophage Xr (1000mg), spread the dose over the day and are gentler on the stomach. Taking metformin with or just after food cuts down on nausea and loose stools. On its own it rarely causes low blood sugar, though vitamin B12 levels can drift down after years of use.
These older tablets push the pancreas to release more insulin, or make the body use it better. Glimepiride is listed as Amaryl (also sold as plain glimepiride; 1mg, 2mg and 4mg), Glipizide as 5mg and 10mg, and Glyburide as Micronase (also sold as plain glyburide) in 2.5mg and 5mg. Low blood sugar (hypoglycaemia: shakiness, sweating, sudden hunger) is the main risk with this class, particularly when a meal is skipped. Actos holds pioglitazone (15mg and 30mg), which can cause fluid retention and weight gain and is not used in heart failure.
Gliptins make the gut hormones that trigger insulin last longer after a meal. Sitagliptin is listed as Sitagliptin and Januvia at 50mg and 100mg, Tradjenta is linagliptin 5mg, and Vsmall is vildagliptin 50mg. They rarely cause low blood sugar by themselves.
Gliflozins work in the kidneys instead, letting the extra sugar leave in the urine. Farxiga (dapagliflozin 5mg and 10mg) is also used for heart failure and chronic kidney disease, and Invokana is canagliflozin 100mg. Expect more frequent urination, and a higher chance of genital thrush and urinary infections.
Semaglutide comes as Rybelsus (also sold as plain semaglutide) in 3mg, 7mg and 14mg tablets, the oral version of the GLP-1 medicines. The 3mg tablet is the starting step, and the dose is raised afterwards. It is taken first thing in the morning on an empty stomach with a small sip of water. Nausea is the common side effect, and it eases for most people.
Combination tablets mean fewer pills a day. Istamet joins sitagliptin and metformin, and Kombiglyze XR joins saxagliptin and metformin. Glyxambi pairs empagliflozin with linagliptin, Actoplus Met pairs pioglitazone with metformin, and Glucovance and Metformin + Glyburide pair glyburide with metformin. Each one carries the side effects of both halves.
PockDose sells metformin as generic Glucophage tablets in 500mg, 850mg and 1000mg, and Glycomet 500mg tablets. It also has semaglutide as generic Rybelsus tablets in 3mg, 7mg and 14mg, dapagliflozin as generic Farxiga tablets in 5mg and 10mg, sitagliptin as generic Januvia tablets in 50mg and 100mg, and generic Glyxambi (linagliptin + empagliflozin) tablets in 25/5mg.
Yes. Sitagliptin comes as generic Januvia tablets in 50mg and 100mg, and dapagliflozin as generic Farxiga tablets in 5mg and 10mg. Combination tablets include generic Glyxambi (linagliptin + empagliflozin) in 25/5mg, generic Kombiglyze XR (saxagliptin + metformin) in 5/500mg and 5/1000mg, and Istamet (sitagliptin + metformin) in 50/1000mg.
Orders arrive in plain, unbranded packaging. Tracked courier takes 5–9 business days; standard airmail takes 14–21 business days and is untracked. See delivery and ordering details.
Yes, both contain metformin and both are listed as 500mg, 850mg and 1000mg tablets. Glucophage is the brand name. The SR and XR versions are separate listings with slower release.
Take one with a small sip of water as the first thing in the day, swallow it whole, then wait at least 30 minutes before eating, drinking or taking other medicines. Food in the stomach stops it being absorbed properly.
They can. Because sugar leaves in the urine, yeast infections of the genitals and urinary infections are more common. Staying hydrated and keeping the area clean and dry helps, and the effect varies from person to person.
Heavy drinking raises the small risk of lactic acidosis, a build-up of acid in the blood, and alcohol can also push blood sugar down. Moderate amounts with food are less of a concern than binge drinking.