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Glyburide is a type 2 diabetes tablet that lowers blood sugar by helping the pancreas release insulin, sold as Micronase 2.5mg and 5mg and in metformin combinations.
Metformin, Glyburide
400/2.50/500/5mg
Glucovance tablets pair metformin with glyburide for type 2 diabetes, available in 400/2.50mg and 500/5mg strengths in packs of 30 to 360 tablets.
Glyburide, Metformin
2.5/400/5/500mg
Metformin + Glyburide combines two oral diabetes medicines in one tablet for type 2 diabetes, sold in 2.5/400mg and 5/500mg strengths.
Glyburide belongs to the sulfonylureas, a family of diabetes medicines that work on the pancreas. It signals the beta cells there to release insulin, the hormone that clears sugar from the blood, and it helps the body make better use of the insulin it already produces. Because of that, it only works when the pancreas still makes some insulin of its own: it suits type 2 diabetes and has no place in type 1 diabetes or diabetic ketoacidosis.
Taken with diet and exercise, and often with other diabetes medicines, it brings blood sugar down. It controls blood sugar rather than curing anything, so it is a long-term medicine.
Tablets, swallowed whole. Most people take one dose a day with breakfast or the first main meal; a second dose with the evening meal is common too. Roughly the same time each day keeps the effect even. Doses tend to start low and are stepped up while blood sugar is still running high.
Sulfonylureas have a habit of fading: after months or years the same dose may not hold blood sugar as well, and the dose or the combination may be changed.
Hypoglycaemia, blood sugar that drops too low, is the one that matters most. Shakiness, sweating, hunger, a racing heartbeat, dizziness, blurred vision and confusion are the usual signs. Glucose tablets or a sweet drink bring a mild episode round; low blood sugar that causes confusion or fainting needs emergency treatment.
Nausea, heartburn and indigestion are the other complaints, and weight often creeps up over time. A rash with swelling of the face or throat is an allergic reaction and needs emergency care.
Alcohol pushes blood sugar down on its own, so a heavy night makes low blood sugar more likely. Aspirin and other salicylates, ibuprofen, naproxen and similar anti-inflammatory painkillers, niacin and cimetidine can all affect blood sugar control alongside it. Bosentan, used for high blood pressure in the lungs, is not combined with it.
Colesevelam, a cholesterol medicine, cuts how much glyburide is absorbed, so glyburide is taken at least four hours before it. People with G6PD deficiency (an inherited condition in which red blood cells break down too easily) are more likely to run into blood problems on a sulfonylurea.
All three glyburide products here are type 2 diabetes treatments, and they sit together in the shop's diabetes range. Micronase is the single-ingredient tablet: glyburide alone, in 2.5mg and 5mg strengths.
The other two put metformin into the same pill. Metformin + Glyburide holds the two ingredients in a single tablet, in two strengths shown on its page. Glucovance is the branded version of that pair, sold here as 400/2.50mg and 500/5mg. Metformin works by a different route: it cuts the sugar the liver releases and helps the body respond to insulin, so the two are often combined when one tablet alone is not enough.
You can order glyburide online with delivery to Hong Kong. The range includes generic Micronase, also sold as Glyburide tablets, in 2.5mg and 5mg, and Metformin + Glyburide and generic Glucovance, which are combination tablets. Payment is by Visa, Mastercard or American Express on a secure, encrypted payment page, or by Bitcoin or Ethereum.
It depends on the product, strength and pack size. Each of the three glyburide products listed here shows its current prices in HKD or the currency you select.
PockDose does not ask you to upload a prescription when you order glyburide. See the ordering FAQ for details.
Micronase is a brand name of glyburide, which is also sold as Daonil and DiaBeta. Here, glyburide can be bought online as generic Micronase. These are generics, not the original brand.
It starts being absorbed within about an hour of a dose, blood levels peak around four hours later, and the blood-sugar-lowering effect of a morning dose lasts roughly 24 hours. That is why one dose a day is enough for many people, while others take a second dose later in the day.
Yes. Micronase is a brand name for glyburide, and the same tablets are also sold under the plain ingredient name in 2.5mg and 5mg. What differs between the two listings is the name on the pack.
Alcohol lowers blood sugar by itself, and glyburide adds to that, so drinking can push sugar too low, sometimes several hours after the last drink. A glass with a meal is one thing; a heavy session is where the risk sits.
It is meant to be taken with food, usually breakfast or the first main meal of the day, so the meal is part of the schedule rather than something to avoid. Skipping a meal while a dose is on board makes low blood sugar more likely.
They are the same medicine under two names. Glyburide is the name used in the United States and Canada; glibenclamide is the name used in the UK, Hong Kong and most other countries. A pack labelled either way contains the same active ingredient.