Capnat
Capnat is capecitabine 500mg in tablet form, an oral chemotherapy medicine for bowel and breast cancer, sold in packs of 100 to 300 tablets.
All strengths and pack prices
| Strength | Pack | Price | Per tablet |
|---|---|---|---|
| 500mg | 100 tablets | $327.00 | $3.27 |
| 500mg | 200 tablets | $630.00 | $3.15 |
| 500mg | 300 tablets | $894.00 | $2.98 |
- Category
- Oncology Support
- Active ingredient
- Capecitabine
- Route
- Oral
- Form
- Tablet
- Strengths
- 500mg
Shipped in a discreet, unmarked envelope.
Details
- Conditions
- Colorectal cancer · Breast cancer
- Therapeutic Class
- Antimetabolite
- Pharmacological Class
- Fluoropyrimidine
- Minor Side Effects
- Diarrhoea, Hand-foot syndrome
- Moderate Side Effects
- Fatigue, Vomiting
- Dosage Forms
- Tablet
- Administration Route
- Oral
- Manufacturer
- Natco Pharma
- Duration
- Per treatment cycle
- Storage Instructions
- Store at room temperature.
- Drug Interactions
- Warfarin, Folic acid
- Age Restrictions
- Adult use only.
FAQ
What pack sizes does Capnat 500mg come in?
Capnat tablets come in 500mg, with packs of 100 to 300 tablets. Larger packs cost less per tablet.
How do I pay for Capnat?
Visa, Mastercard or American Express on an encrypted page, so your card number never reaches our servers, or Bitcoin or Ethereum if you prefer to keep the payment off your card.
What other names is capecitabine sold under?
Capnat is a branded generic of capecitabine, the ingredient in Xeloda. Here, capecitabine can be bought online as Capnat, and also as generic Xeloda. These are generics, not the original brand.
Is Capnat the same as Xeloda?
Yes. Capnat and Xeloda are two brand names for capecitabine, and each pack holds 500mg tablets used for bowel and breast cancer. The main differences are the box and the name printed on it.
How long does a cycle of Capnat last?
Three weeks from start to start: 14 days on tablets, 7 days off. How many cycles follow is set by the cancer and how it responds, and a full course often runs for several months.
What is hand-foot syndrome?
A reaction of the palms and soles that starts as redness or tingling and can progress to swelling, soreness and peeling. It is among the commonest capecitabine effects. Rich moisturiser, soft shoes and avoiding very hot water help, and it generally settles in the week off tablets.
Can Capnat be taken with other chemotherapy drugs?
Other fluoropyrimidines such as 5-fluorouracil or tegafur cannot be added, since they act the same way and their effects would stack. Cancer drugs from other groups are often combined with capecitabine.
How does Capnat compare with intravenous 5-fluorouracil?
5-fluorouracil is the active drug capecitabine turns into in the body. The difference is the route: 5-fluorouracil is given into a vein, while capecitabine is swallowed at home as tablets.
About Capnat
What Capnat is for
For someone who would rather not spend hours attached to a drip, Capnat is chemotherapy swallowed at home: capecitabine in 500mg tablets. Bowel cancer, whether it began in the colon or the rectum, and breast cancer are its main uses. It is also used in cancers of the stomach, the food pipe (oesophagus) and the pancreas. Packs hold 100 to 300 tablets.
How the tablet switches on
Swallowed, capecitabine does nothing at first. Enzymes in the liver and then in tissue convert it step by step into 5-fluorouracil, which stops cancer cells from copying their DNA and so from dividing. Because the final conversion happens mostly within the tumour, much of the active drug ends up there. The body clears the remainder through the urine.
Two weeks on, one week off
A cycle runs 14 days of tablets followed by 7 days without, and it repeats for as many rounds as have been planned. On the days with tablets there are two doses, about twelve hours apart and each just after food, so breakfast and the evening meal do the reminding. The tablets go down whole with water; one that has been cut or chewed releases powder that can irritate the eyes and skin. If a dose is vomited straight back up, wait for the next scheduled one and skip the replacement. A dry spot out of sunlight suits the pack.
Common effects and urgent ones
By the second week of a cycle, many people have loose stools, a sore mouth, little appetite and a tired, queasy feeling; the week without tablets is when these tend to ease. The palms and soles may turn red, swell or peel, which is called hand-foot syndrome. Blood counts can drop, so infections come more easily and bruises show up. Diarrhoea that is severe, a fever with shivering, or bleeding that does not stop needs urgent treatment. Two things carry extra danger. Warfarin can cause serious bleeding when combined with capecitabine, and people short of the enzyme DPD, which breaks the drug down, can be harmed by an ordinary dose.
Capnat or Xeloda?
The tablets inside are the same, 500mg of capecitabine for bowel and breast cancer, and only the brand name on the box differs. Xeloda is the other brand of this medicine, and the ingredient page for both is capecitabine.
Sources
- Capecitabine: MedlinePlus Drug Information — MedlinePlus / U.S. National Library of Medicine
- Capecitabine | Macmillan Cancer Support — macmillan.org.uk