Tivicay
Tivicay is generic dolutegravir 50mg tablets for HIV-1 infection, taken once a day alongside other antiretrovirals to cut the amount of virus in the blood.
All strengths and pack prices
| Strength | Pack | Price | Per tablet |
|---|---|---|---|
| 50mg | 30 tablets | $117.00 | $3.90 |
| 50mg | 60 tablets | $187.20 | $3.12 |
| 50mg | 90 tablets | $252.00 | $2.80 |
| 50mg | 120 tablets | $328.80 | $2.74 |
- Category
- HIV Management
- Active ingredient
- Dolutegravir
- Route
- Oral
- Form
- Tablet
- Strengths
- 50mg
You will receive a quality generic equivalent, depending on stock.
Shipped in a discreet, unmarked envelope.
Details
- Conditions
- HIV-1 infection
- Therapeutic Class
- Antiretroviral
- Pharmacological Class
- Integrase Inhibitor
- Minor Side Effects
- Insomnia, Fatigue
- Moderate Side Effects
- Dizziness, Nausea
- Dosage Forms
- Tablet
- Administration Route
- Oral
- Originator
- ViiV Healthcare
- Storage Instructions
- Store at room temperature.
- Drug Interactions
- Dofetilide, Etravirine
- Age Restrictions
- Consult doctor for paediatric use.
What you will receive
Tivicay is the originator brand name, made by ViiV Healthcare. We use it to identify the medicine; the pack you receive is a generic equivalent, not the original Tivicay.
- The same active ingredient (Dolutegravir) at the same strength.
- The exact brand supplied depends on what is in stock when your order ships.
FAQ
What pack sizes of Tivicay can I order?
50mg tablets, in packs of 30, 60, 90 or 120, which is one to four months at one a day. They are generic dolutegravir, not the original Tivicay, and each tablet costs less in the bigger packs.
How discreet is a Tivicay delivery to Hong Kong?
Every Tivicay order ships in plain, unbranded packaging, with nothing on the outside about the contents. Tracked courier takes 5 to 9 business days and includes online tracking. If a parcel goes missing within the delivery window, it is sent again free, or refunded if that is not possible.
Can I take antacids or iron tablets with Tivicay?
Keep them apart. Antacids, calcium and iron supplements, multivitamins and sucralfate bind dolutegravir in the gut, so take Tivicay two hours before them or six hours after them. The one exception is a dose taken with a meal, when calcium or iron supplements can go alongside it.
Can I drink alcohol with Tivicay?
There is no known interaction between dolutegravir and alcohol, so an occasional drink is not a problem. Heavy drinking is a different matter: it puts strain on the liver and makes it easy to forget a daily tablet, and missed doses are what let HIV regain ground.
Does Tivicay make the pill or other hormonal contraception less effective?
No. Dolutegravir does not interfere with the pill, the patch, the ring or the implant, so your usual method keeps working as before. It is not one of the medicines that speed up how the body clears contraceptive hormones.
Can Tivicay be taken with other HIV medicines?
Yes, and it usually is. Dolutegravir is commonly the third drug in a three-drug regimen, taken with two nucleoside reverse transcriptase inhibitors such as tenofovir with emtricitabine, or abacavir with lamivudine. When treatment is being switched, it can be paired with other classes instead.
How does Tivicay compare with other integrase inhibitors?
Dolutegravir stays in the body longer than elvitegravir, which is why it works as a once-a-day tablet without a booster. Elvitegravir is normally taken with cobicistat, a booster that keeps its levels high enough between doses.
About Tivicay
Tivicay 50mg for HIV-1
The 50mg tablets sold here are generic dolutegravir, not the original brand. Dolutegravir is an integrase inhibitor, a class of HIV medicine used against HIV-1 infection in adults and children, and it goes into a regimen with other antiretrovirals rather than being used by itself. There is no cure for HIV; the aim of treatment is to keep the virus suppressed so the immune system can recover and AIDS-related illness becomes far less likely.
How dolutegravir works
Once HIV is inside a human cell, it uses an enzyme called integrase to stitch its own genetic material into the cell's DNA. That step is what turns an infected cell into a virus factory. Dolutegravir blocks integrase, so the viral code never joins the cell's DNA and the virus cannot copy itself. With each dose the amount of virus circulating in the blood falls a little further.
Taking Tivicay
Most adults take one 50mg tablet once a day; some regimens call for twice-daily dosing instead, depending on resistance and on which other medicines are being used. Swallow the tablet whole with water. It can be taken with a meal or on an empty stomach, but keep to roughly the same time each day so the level in the blood stays steady. Missing doses gives the virus room to multiply and can make the infection harder to treat later. Keep the blister strips in their outer pack, somewhere out of the heat.
Side effects to watch for
Headache, difficulty sleeping, tiredness, nausea and diarrhoea are the complaints people report most often, and for many they settle after the first few weeks. Dolutegravir has been linked with low mood and, in some cases, thoughts of self-harm, more often in people who have had mental health problems before. A rash with fever, or swelling of the face, lips or throat, is a severe allergic reaction and needs urgent treatment.
What interferes with Tivicay?
Antacids, laxatives, multivitamins, calcium and iron supplements, sucralfate and buffered medicines such as buffered aspirin all bind dolutegravir in the gut and lower how much of it reaches the blood. Leave a gap of a few hours between these and the tablet. St John's wort is the one herbal product to avoid altogether: it drops dolutegravir levels sharply. Rifampicin, used for tuberculosis, and the epilepsy medicines carbamazepine and phenytoin have a similar effect and usually mean a twice-daily schedule.
Sources
- Dolutegravir: MedlinePlus Drug Information — National Library of Medicine
- About HIV - CDC — Centers for Disease Control and Prevention