Doxylamine Succinate
Doxylamine succinate is the antihistamine paired with vitamin B6 to calm the nausea and vomiting of pregnancy; this page lists Diclegis 10/10mg delayed-release tablets.
An older antihistamine that settles the stomach
Doxylamine succinate belongs to the first-generation antihistamines — the older group that blocks histamine and, in most people, brings on sleepiness. It also dampens the nausea reflex in the brain, which is why it helps with the sickness of early pregnancy and with queasiness linked to balance. In some countries the ingredient is sold on its own as a short-term sleep aid. The listing on this page uses it for morning sickness, paired with vitamin B6.
Diclegis, the one listing
Diclegis is the only tablet here: 10mg doxylamine succinate with 10mg pyridoxine (a form of vitamin B6) in a delayed-release coating that lets the dose out over several hours. A tablet taken at bedtime is therefore still working overnight. You will find it in women's health.
How it is taken
Swallow the tablet whole with water. Crushing or chewing a delayed-release tablet releases the full dose in one go, which is not how it is meant to work. Most people start with a tablet at bedtime, since drowsiness is part of the effect and night-time is when it does most good; when nausea runs through the day as well, a dose can be moved earlier, with one in the morning and another in the afternoon. You do not have to time it around meals. Keep the pack somewhere dry and away from heat, and do not use tablets past the date on the box.
Side effects to expect
Sleepiness is the one most people notice, and it often lingers into the morning. A dry mouth, dizziness, blurred vision, constipation and a blocked nose are common too and usually ease as the body adjusts. Doxylamine can make an enlarged prostate, trouble passing urine or narrow-angle glaucoma worse, and older adults may feel confused or unsteady. Taking more than the pack says does not make it work better and simply deepens the drowsiness. A rash with swelling of the face or throat, or difficulty breathing, is a rare allergic reaction and needs urgent treatment.
Alcohol and other sedating medicines
Alcohol stacks with doxylamine's sleepiness and can leave you dizzy, unsteady and slow the next day. Opioid painkillers, benzodiazepines, sleeping tablets and some antidepressants add to the effect in the same way. Until you know how a dose treats you, driving and machinery are best avoided.
Sources
- Doxylamine: MedlinePlus Drug Information — National Library of Medicine
- PHARMACY CHOICE DOXYLAMINE doxylamine succinate 25 mg tablet blister pack (new formulation) | Therapeutic Goods Administration (TGA) — Therapeutic Goods Administration
Can I order Doxylamine Succinate online in Hong Kong?
Doxylamine Succinate can be ordered online for delivery to Hong Kong. The page carries generic Diclegis tablets as a combination tablet of 10/10mg. A parcel that does not arrive within its delivery window, or arrives damaged, is sent again free, and where that is not possible the order is refunded.
What is the price of Doxylamine Succinate?
Diclegis is priced per pack: its page lists every strength and pack size with the current price in HKD or your chosen currency.
Do I need a prescription to order Doxylamine Succinate?
PockDose does not ask you to upload a prescription when you order doxylamine succinate. See the ordering FAQ for details.
What is another name for doxylamine succinate and pyridoxine?
Diclegis is a brand name of doxylamine succinate and pyridoxine, which are also sold as Doxinate. Here, doxylamine succinate and pyridoxine can be bought online as generic Diclegis. These are generics, not the original brand.
Is doxylamine succinate the same as a sleeping tablet?
It is an antihistamine rather than a purpose-built sleeping tablet, but it makes most people drowsy. Some countries sell it on its own for short-term sleeplessness; the listing here combines it with vitamin B6 for the nausea and vomiting of pregnancy.
What does 10/10mg mean on the Diclegis listing?
The two numbers are the amounts of each active ingredient in one tablet: 10mg of doxylamine succinate and 10mg of pyridoxine, which is a form of vitamin B6. The combination comes in that single strength here.
Can I drink alcohol with doxylamine succinate?
Alcohol adds to the drowsiness doxylamine already causes, and the two together can leave you dizzy, unsteady and slow the next day. Keeping the amount small, and seeing how you feel before driving or using machinery, avoids most of the trouble.
Should I take doxylamine succinate with food?
A meal is not needed before a dose, and food does not change much about how the tablet works. What matters more is keeping to the same pattern each day, usually at bedtime, and swallowing the delayed-release tablet whole rather than splitting or chewing it.
What is the difference between doxylamine succinate and pyridoxine?
Doxylamine succinate is the antihistamine half, and it is the part that causes drowsiness; pyridoxine is vitamin B6, which is used by itself for pregnancy sickness. Diclegis puts both into one delayed-release tablet.