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Galantamine is an acetylcholinesterase inhibitor taken twice a day for the symptoms of mild to moderate Alzheimer's disease, sold here as 4mg and 8mg tablets.
Galantamine
4/8mg
Galantamine tablets in 4mg and 8mg strengths, an acetylcholinesterase inhibitor taken twice a day with food for the symptoms of Alzheimer's disease.
Someone searching for galantamine is usually looking for help with Alzheimer's disease, where memory slips, thinking gets muddled and behaviour can change. The tablets are meant for the mild to moderate stages. They ease those symptoms for as long as they are taken, but the disease itself carries on. We sell galantamine tablets in 4mg and 8mg, and other medicines for the brain and nerves sit in the neurology range.
Nerve cells pass messages with acetylcholine, a chemical messenger used in memory and learning. An enzyme, acetylcholinesterase, normally clears it away once it has done its job, and in Alzheimer's disease there is too little of it available for signalling. Galantamine blocks that enzyme, leaving more acetylcholine in place, and it also acts on nicotinic receptors — docking points on nerve cells — to nudge the release of other messengers. Signalling between the cells that are still working becomes steadier.
Breakfast and the evening meal are the two moments to build around: one tablet with each, at much the same times every day, and food takes the edge off the stomach upset they can cause. Water through the day helps as well. Treatment normally begins at the lower strength and climbs in steps, at least four weeks between each rise, so 4mg is where many people start and 8mg comes later. If a dose slips your mind, let it go and wait for the next one rather than doubling up. Keep the pack in its box, somewhere cool and dry.
Nausea, vomiting, diarrhoea, going off food and losing some weight are the commonest complaints, joined by dizziness, headache, tiredness and broken sleep. They tend to be worst in the early weeks and after each dose step, and a meal with the tablet helps. A few effects are not routine: an unusually slow, pounding or irregular heartbeat, fainting, a seizure, trouble passing urine, or a flare of asthma-type breathing difficulty. Black or tarry stools, or vomit with blood in it, point to bleeding in the stomach or gut and need urgent treatment.
Medicines that dry up acetylcholine work against it — the antihistamines diphenhydramine and chlorphenamine, the travel-sickness tablets meclizine and dimenhydrinate, and the antidiarrhoeal loperamide. Beta-blockers, used for blood pressure and heart rhythm, can add to its heart-slowing effect. Aspirin, ibuprofen and naproxen raise the chance of a stomach ulcer or bleeding when taken alongside galantamine, and cimetidine, used for heartburn, can push its levels up.
Galantamine can be ordered online with delivery to Hong Kong. The range is Galantamine tablets in 4mg and 8mg. Tracked courier delivery takes 5 to 9 business days and comes with online tracking.
Galantamine is priced per pack: its page lists every strength and pack size with the current price in HKD or your chosen currency.
PockDose does not ask you to upload a prescription when you order galantamine. See the ordering FAQ for details.
Reminyl is a brand name of galantamine, which is also sold as Razadyne. Here, galantamine can be bought online as galantamine tablets. These are generics, not the original brand.
No. Galantamine eases the symptoms of mild to moderate Alzheimer's disease and keeps them steadier for as long as it is taken, but it does not cure the condition or reverse the changes in the brain. Any benefit is judged over weeks rather than days.
Improvement is slow and measured in weeks. The dose is raised in steps at least four weeks apart, so the strength that suits you may not be reached for a month or two, and what you notice is a steadier level of memory and thinking rather than a sudden change.
They hold the same ingredient in different amounts and are both taken twice a day with food. 4mg is the strength treatment usually starts on; 8mg is a later step, once the lower dose is going down without troublesome side effects.
Ibuprofen, naproxen and aspirin all raise the chance of a stomach ulcer or bleeding in the gut when taken with galantamine. That risk is higher again in anyone who has had an ulcer or stomach bleeding before.
They are different medicines from the same class, acetylcholinesterase inhibitors, and both are used for mild to moderate Alzheimer's symptoms. Donepezil is taken once a day, while galantamine tablets are taken twice a day, so the two are not swapped strength for strength.