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Lenalidomide is a once-daily capsule used in multiple myeloma and myelodysplastic syndromes, sold here as 10mg capsules in packs for a course of treatment.
Lenalidomide
10mg
Lenalidomide 10mg capsules: an immunomodulatory medicine for multiple myeloma and myelodysplastic syndromes, taken in repeating cycles to help the immune system attack abnormal blood cells.
Lenalidomide is used to treat multiple myeloma, a cancer that begins in the plasma cells of the bone marrow, and myelodysplastic syndromes, where the marrow stops producing enough healthy blood cells. It also has a role in mantle cell lymphoma and follicular lymphoma, two cancers of the lymph nodes, when earlier treatment has not been enough. In myelodysplastic syndromes it is used in people whose marrow cells are missing part of chromosome 5; in that group it can reduce how often blood transfusions are needed. Lenalidomide is never taken during pregnancy, because it can cause severe birth defects.
It belongs to the immunomodulatory drugs, the family that includes thalidomide. Inside the cell, lenalidomide attaches to a protein called cereblon and steers it to break down certain other proteins — ones that abnormal plasma cells depend on to keep multiplying. Robbed of those signals, the cells stop dividing and die. Lenalidomide also alters the marrow's support system, including the small blood vessels that would otherwise feed a growing cluster of abnormal cells, and it helps the immune system recognise them. Because healthy blood cells are made in the same marrow, counts of red cells, white cells and platelets often fall while treatment continues.
Lenalidomide capsules are made in several strengths; the one sold here is Lenalidomide 10mg. A capsule is taken once a day, swallowed whole with water rather than opened, crushed or chewed, and it is worth keeping to a steady time so the routine sticks. How long treatment continues is decided cycle by cycle rather than fixed at the start, and blood counts are checked as it goes. Keep the capsules in the pack they came in.
Diarrhoea, constipation, nausea, rash, itching, tiredness and swelling of the hands or ankles are the effects people most often notice, and they tend to ease as the body adjusts. Dips in blood counts are expected rather than unusual. Less common but more serious are blood clots in the leg or lung, and severe skin reactions. A painful, swollen calf, chest pain or sudden breathlessness is a clot until proven otherwise and needs treatment straight away. Digoxin, used for the heart, is the interaction to know about with lenalidomide.
Lenalidomide can be ordered online with delivery to Hong Kong. The product here is Lenalidomide capsules in 10mg. An order can be cancelled within 24 hours if it has not been dispatched, and support answers around the clock in English and Cantonese.
Lenalidomide is priced per pack: its page lists every strength and pack size with the current price in HKD or your chosen currency.
Lenalidomide is sold under brand names including Lenalid and Revlimid. Here, lenalidomide can be bought online as lenalidomide capsules. These are generics, not the original brand.
Digoxin is the medicine noted as interacting with lenalidomide. Lenalidomide capsules in 10mg are sold here.
Lenalidomide can be taken with a meal or on an empty stomach. Keeping to a steady daily routine matters more than the food question, so it helps to tie the capsule to something you already do, such as breakfast or brushing your teeth at night.
Treatment runs in cycles rather than a set number of days: usually 21 days of a capsule each day, then 7 days without, then the pattern starts again. The total number of cycles depends on the condition being treated and how well it responds.
No. They belong to the same family of immunomodulatory drugs and share the serious risk of birth defects, but they are separate medicines. Lenalidomide is taken at different strengths and on a different schedule, and it is used mainly in multiple myeloma and related blood conditions.
Yes. Red cells, white cells and platelets often fall during lenalidomide treatment, because the marrow where they are made is the same place the medicine acts. A low white cell count makes infections more likely, and a low platelet count makes bruising or bleeding easier. Blood tests track the counts as treatment goes on.
Response is judged over the first cycles rather than days. Regular blood tests show what the marrow is doing, and in myeloma the level of abnormal protein in blood or urine is tracked to see how well the disease is answering treatment. The results decide whether the schedule continues unchanged.