Raloxifene

Raloxifene is a once-daily tablet that treats and prevents osteoporosis after the menopause and lowers invasive breast cancer risk, sold here as 60mg tablets.

Raloxifene

Raloxifene

60mg

Raloxifene 60mg tablets for osteoporosis after the menopause and to lower the risk of invasive breast cancer in high-risk women, in packs of 10 to 360.

from $1.02 / tablet View

What raloxifene treats

Raloxifene treats and prevents osteoporosis — bone that has thinned and become easy to break — in women past the menopause. It is also taken by postmenopausal women at higher risk of invasive breast cancer (cancer that has grown beyond the milk ducts into nearby tissue) to lower that risk. It is not a treatment for breast cancer that has already developed, and it is not given to women who have not yet been through the menopause. The 60mg tablets are the form sold here, in the women's health and bone support ranges.

How raloxifene acts on bone

It belongs to a class called selective oestrogen receptor modulators, or SERMs. Oestrogen normally slows the breakdown of bone, and levels of it drop after the menopause, which is when bone loss speeds up. Raloxifene switches on oestrogen receptors in bone, so bone is broken down more slowly and mineral density is kept up. In breast tissue it does the opposite: it blocks oestrogen's signal, which is how it lowers the chance of an oestrogen-dependent tumour starting. In the womb it has no oestrogen-like effect at all.

How do you take the tablets?

One 60mg tablet a day. Food makes no difference — a meal or an empty stomach are both fine — but keep to a regular point in the day so the amount in your body stays steady. Raloxifene is a long-term medicine, so the benefit lasts only while you keep taking it.

Common side effects

Hot flushes are the most common one, reported by more than one woman in ten in the main studies, and flu-like symptoms are also frequent. Swelling of the hands, feet or ankles, leg cramps and joint pain turn up too.

Blood clots and other risks

Raloxifene raises the chance of a clot forming in a deep vein, usually in the leg, or breaking loose and travelling to the lungs. Sitting still for hours on a long flight or car journey, or being confined to bed, adds to that chance. Pain, warmth or swelling in one calf, sudden breathlessness, chest pain or coughing up blood needs urgent treatment, as does any sudden change in vision. Raloxifene is not used by anyone who has had a clot, or who has liver disease, severe kidney problems, unexplained bleeding from the womb or cancer of the womb lining, and it is not taken during pregnancy. Two interactions matter: cholestyramine cuts how much raloxifene is absorbed, and warfarin's effect on clotting can shift while raloxifene is taken.

Sources

  1. Raloxifene: MedlinePlus Drug Information — MedlinePlus / U.S. National Library of Medicine
  2. Evista | European Medicines Agency (EMA) — European Medicines Agency
Where can I buy Raloxifene in Hong Kong?

Raloxifene can be ordered online from PockDose with delivery to Hong Kong. The page lists plain Raloxifene tablets in 60mg as the only version here. Orders leave in plain, unbranded packaging, with nothing on the outside to say what is inside.

What is the price of Raloxifene?

The price depends on the strength and pack size you choose. The Raloxifene page shows current prices in HKD or the currency you select.

Do I need a prescription to order Raloxifene?

PockDose does not ask you to upload a prescription when you order raloxifene. See the ordering FAQ for details.

What is another name for raloxifene?

Raloxifene is sold under brand names including Evista. Here, raloxifene can be bought online as raloxifene tablets. These are generics, not the original brand.

Does raloxifene prevent breast cancer?

It lowers the risk of invasive breast cancer in postmenopausal women who are at higher risk of it or who also have osteoporosis. It is not used once breast cancer has been diagnosed, it will not keep it from coming back, and it does not lower the risk of the non-invasive kind, which stays inside the milk ducts.

What strength are the raloxifene tablets?

60mg, taken as one tablet a day — the standard strength for this medicine and the only one sold here. There is no lower or higher version to choose between, so ordering comes down to how many packs you want rather than which strength.

Does raloxifene cause hot flushes?

Yes. Hot flushes are the most common side effect, reported by more than 1 in 10 women in the largest trials, and flu-like symptoms are common too. Swollen hands, feet or ankles, leg cramps and joint pain also turn up. Not everyone notices them.

How long do you take raloxifene for?

There is no fixed course length — raloxifene is intended for long-term use, and bone changes are tracked over years rather than weeks. That is why it is taken every day rather than now and then.

Should I take calcium and vitamin D with raloxifene?

Calcium and vitamin D are often taken alongside raloxifene when the diet does not supply enough of either, but they are separate supplements rather than ingredients of the tablet. Taking them does not change how the raloxifene is taken.