Digoxin
Digoxin

0.44
Digoxin is a medication used to manage chronic heart conditions, including heart failure and atrial fibrillation, by regulating heart rhythm and contractility.


Ingredient
Availability
In Stock
Delivery
Airmail (14-21 days) | EMS trackable (5-9 days)
Product is shipped in a fully discreet envelope with no content disclosure, including all required documentation inside

Product Sheet

Active Ingredient(s)
Digoxin
Reference Brand
Digoxin
Product Origin
Generic Product
Reference Manufacturer
GSK
Product Form
Tablet, Injection
Regulatory Classification
Rx
Primary Category
Heart & Blood Pressure
Product Category
Cardiac glycoside
Pharmacological Class
Inotrope
Clinical Indications
Heart failure, Atrial fibrillation
Manufacturer Description
Digoxin is a medication used to manage chronic heart conditions, including heart failure and atrial fibrillation, by regulating heart rhythm and contractility.
Mechanism of Action
Digoxin inhibits the sodium-potassium pump in cardiac muscle cells, increasing intracellular calcium to strengthen heart contractions and slow the heart rate.
Route of Administration
Oral
Onset Time
1–2 hours
Duration
36–48 hours
Contraindications
Ventricular fibrillation, Hypersensitivity
Severe Adverse Events
Cardiac arrhythmias, Severe electrolyte imbalance, Potassium toxicity
Common Side Effects
Nausea, Dizziness, Fatigue
Uncommon Side Effects
Visual disturbances, Headache, Confusion
Drug Interactions
Amiodarone, Verapamil, Diuretics
Pregnancy Safety Warnings
Use only when necessary.
Age Restrictions
Use with extreme caution in seniors.
Storage Guidelines
Store at room temperature in a dry place.
Related Products
Digitoxin

Digoxin FAQ

Can digoxin be taken with other heart medications like beta-blockers?

Yes, digoxin is often prescribed together with beta-blockers to achieve complementary rate control in atrial fibrillation. However, the combination can increase the risk of bradycardia, so dose adjustments and close monitoring are advisable.

What should I do if I notice a yellow-green halo around lights?

Visual disturbances such as a yellow-green halo are classic signs of digoxin toxicity. Contact your healthcare provider promptly for evaluation and possible serum level testing.

Is there a difference between generic digoxin and brand-name versions?

Both generic and brand-name formulations contain the same active ingredient, digoxin, and must meet identical quality standards. Inactive ingredients may differ slightly, which can affect tolerability in a small number of patients.

How long does it take for digoxin to reach steady-state levels?

Steady-state concentrations are usually achieved after 6-7 days of consistent dosing, given the drug’s half-life of about 36-48 hours in individuals with normal renal function.

Can I travel internationally with my digoxin prescription?

Yes, but you should carry the original prescription label, a copy of the prescribing doctor’s note, and keep the medication in its original container. Some countries may require additional documentation for controlled substances.

Are there any foods that should be avoided while taking digoxin?

High-fiber meals can modestly reduce digoxin absorption, while large amounts of caffeine may increase heart rate. Maintaining a consistent diet helps keep drug levels stable.

What is the impact of low potassium on digoxin therapy?

Hypokalemia enhances digoxin’s binding to the sodium-potassium pump, raising the risk of toxicity. It is important to correct low potassium levels before or during digoxin treatment.

Do I need to have my blood tested for digoxin levels regularly?

Routine serum digoxin monitoring is recommended after dose initiation, after any dose change, and periodically thereafter, especially in patients with renal impairment or concurrent interacting medicines.

How should digoxin be disposed of when it expires?

Do not flush digoxin tablets down the toilet. Return unused or expired medication to a pharmacy’s take-back program or follow local hazardous-waste disposal guidelines to prevent accidental ingestion.

What is Digoxin?

Supporting the heart's pumping efficiency, Digoxin serves as a cardiac glycoside frequently utilized to assist with specific rhythm disturbances and heart failure. This active compound functions by influencing the movement of electrolytes like calcium and sodium within heart muscle cells to help maintain a more regular and organized contraction pattern.

It is the primary active substance found in formulations such as Lanoxin. As an agent with long-standing clinical history, it remains a common choice for managing symptoms that interfere with the heart's ability to circulate blood throughout the body effectively.

Healthcare providers in Hong Kong often rely on this substance to help patients who experience persistent fatigue or fluid retention associated with a compromised cardiovascular system. By encouraging more efficient cardiac output, it acts on the underlying mechanics of how the heart muscle reacts to electrical signals.

Formulations and Clinical Products

Digoxin is delivered through various formulations, including oral tablets and concentrated liquids, to accommodate different patient needs. In the landscape of Hong Kong healthcare, this API appears in both original branded products and locally available generic alternatives.

Generic versions undergo rigorous testing to ensure they contain the same active amount of the compound as their branded counterparts. Patients might notice variances in the color, shape, or inactive fillers between different versions of the medication, though the therapeutic activity of the API remains consistent across these standardized inputs.

Therapeutic Applications

  • Heart Failure Management: This substance supports the heart in pumping blood more effectively, which helps reduce symptoms like swelling or shortness of breath.
  • Atrial Fibrillation: It is often applied to assist in controlling the heart rate, particularly when resting levels are higher than necessary.
  • Improving Exercise Tolerance: By stabilizing cardiac function, the compound can help patients participate in moderate physical activities with less exhaustion.
  • Symptom Relief: It addresses the physiological strain on the body caused by an inefficient cardiovascular system, helping to manage fluid accumulation in the limbs or lungs.

Influence on Cardiac Function

Applying pressure to the heart's electrical and mechanical systems, Digoxin increases the strength of each heartbeat while facilitating a slower, more deliberate rhythm. It achieves this by modulating the ion exchange pumps found on the membranes of cardiac muscle cells.

When calcium levels inside these cells increase, the muscle fibers become more efficient at contracting. Simultaneously, the substance signals the nervous system to dampen excessive electrical impulses traveling to the heart. This combination helps transition a rapid or irregular heartbeat into a more productive and balanced state.

Safety Profile

Common Reactions

Patients may occasionally experience mild nausea, loss of appetite, or general fatigue as the body adjusts to the substance. These patterns are often transient and tend to subside as the system stabilizes under a consistent routine.

Serious Reactions

Immediate attention is necessary if individuals notice signs of confusion, distinct visual changes such as blurred vision or halos around lights, or a significantly irregular pulse. These indicators suggest the need for a clinical review of how the substance is currently interacting with the body's baseline levels.

Contraindications

Individuals with specific electrical conduction issues in the heart, known as heart block, typically avoid this compound. Furthermore, those with severe electrolyte imbalances, particularly low potassium levels, require specialized monitoring before and during the use of this substance.

Interaction Awareness

A wide variety of substances, including certain diuretics, calcium channel blockers, and herbal supplements like St. John’s Wort, can alter how the body processes this medication. For an exhaustive and personalized list of interactions pertinent to your specific formulation, always review the medication’s provided clinical information leaflet.

Usage Considerations

Consistent timing is vital, as the substance relies on maintaining steady levels in the bloodstream to effectively manage cardiac rhythm. Most individuals follow a long-term treatment plan, though adjustments are frequently made based on blood tests conducted by a medical professional. For detailed usage, dosing, and administration, refer to the specific medication's clinical information.

Glossary

Cardiac Glycoside
A class of substances derived from plants that increase the force of heart muscle contraction and improve efficiency.
Atrial Fibrillation
A condition characterized by an irregular and often rapid heart rate that can lead to poor blood flow.
Electrolytes
Essential minerals like potassium and calcium that carry an electric charge and are vital for proper nerve and muscle function.

Clinical Disclosure for Digoxin

This document provides a factual overview of Digoxin for educational purposes and does not constitute medical advice or a diagnosis. Because medications like Lanoxin vary significantly in their formulation, strength, and individual administration requirements, clinical decisions must be individualized. We disclaim all liability regarding the use of this information in a clinical setting. Always review the specific product labeling provided with your medicine and consult a licensed healthcare professional in Hong Kong before adjusting therapy.

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