Duphaston
Duphaston

2.13
Duphaston is a hormone supplement utilized for managing various hormonal imbalances and menstrual irregularities in women.


Ingredient
Availability
In Stock
Delivery
Airmail (14-21 days) | EMS trackable (5-9 days)
Product is shipped in a fully discreet envelope with no content disclosure, including all required documentation inside

Product Sheet

Active Ingredient(s)
Dydrogesterone
Reference Brand
Duphaston
Product Origin
Generic Brand
Product Manufacturer
Abbott
Product Form
Tablet
Regulatory Classification
Rx
Primary Category
Women's Health
Product Category
Progestogen
Pharmacological Class
Synthetic steroid
Clinical Indications
Menstrual cycle disorders, Endometriosis
Manufacturer Description
Duphaston is a hormone supplement utilized for managing various hormonal imbalances and menstrual irregularities in women.
Mechanism of Action
Dydrogesterone acts as a progestogen to correct hormone deficiencies, regulating the menstrual cycle and supporting uterine tissue health.
Route of Administration
Oral
Onset Time
Varies by condition
Duration
24 hours
Contraindications
Undiagnosed vaginal bleeding, Breast cancer
Severe Adverse Events
Liver function changes
Common Side Effects
Headache, Nausea
Uncommon Side Effects
Breast tenderness, Skin rash
Drug Interactions
Liver enzyme inducers
Pregnancy Safety Warnings
Use only if advised by a doctor.
Storage Guidelines
Store in a dry place.
Related Products
Medroxyprogesterone

Duphaston FAQ

Can Duphaston be used for birth control?

Duphaston is not indicated as a contraceptive. While it contains a progestogen, effective birth control requires a formulation specifically approved for that purpose and a dosing schedule that maintains consistent ovulation suppression.

What should I do if I experience heavy vaginal bleeding while taking Duphaston?

Heavy or prolonged bleeding may signal an underlying hormonal imbalance or a rare adverse reaction. Contact your prescriber promptly; they may adjust the dose, suggest additional investigations, or switch to an alternative therapy.

Does Duphaston interact with herbal supplements such as St. John’s Wort?

St. John’s Wort is a known CYP3A4 inducer and can reduce dydrogesterone levels, potentially diminishing therapeutic effect. Discuss all herbal products with your healthcare provider before starting Duphaston.

Is Duphaston safe for women with a history of migraines?

Most women with migraine can use dydrogesterone, but if migraines are accompanied by aura, hormonal fluctuations could exacerbate symptoms. Monitor migraine patterns and seek medical advice if they worsen.

Can I travel internationally with Duphaston tablets?

Yes, but keep the medication in its original packaging with a copy of the prescription. Some countries may require proof of medical necessity for hormonal drugs; carrying a doctor’s note can help avoid customs delays.

What does the imprint on a Duphaston tablet look like?

In most markets, a 10 mg Duphaston tablet bears the imprint “DUP 10”. Appearance may vary slightly by manufacturer, so verify the imprint against the pharmacy label.

Are there any dietary restrictions while taking Duphaston?

There are no specific food prohibitions. Taking the tablet with a meal can ease gastrointestinal discomfort, but high-fat meals may delay absorption slightly, which is usually clinically insignificant.

How long does it take for menstrual irregularities to improve after starting Duphaston?

Most women notice a more regular cycle within 1-2 months of consistent daily dosing, although the exact timeline depends on the underlying condition and individual response.

Can Duphaston affect results of hormone-based drug tests at work?

Standard workplace drug screens do not test for progestogens. However, specialized endocrine testing (e.g., for doping control) might detect synthetic progesterone metabolites; inform the testing agency if you are under medication.

Is there a generic version of Duphaston available in Hong Kong?

Yes, dydrogesterone is marketed under various generic names. The active ingredient and dosage are identical, though tablet imprint and packaging may differ. Always obtain medication from a licensed pharmacy.

What is Dydrogesterone?

Functioning as a synthetic progestogen, dydrogesterone assists in mimicking the physiological effects of natural progesterone within the human body. This active compound resides as a core ingredient in formulations such as Duphaston, addressing various reproductive health conditions. By maintaining a molecular structure similar to female hormones, it provides a stable endocrine-supportive effect in situations where natural progesterone levels require supplementation.

This compound serves as a key active component in managing complex hormonal cycles. Dydrogesterone is distinct from other progestogens, as it possesses a highly specific receptor profile that minimizes impact on other endocrine systems. It remains a widely identified substance in Hong Kong clinical practice for maintaining hormonal balance during specific phases of the reproductive cycle.

Clinical Formulations and Delivery

Dydrogesterone is typically encountered in tablet form, designed for consistent oral administration. In the Hong Kong medical landscape, it is categorized as a specific hormonal formulation that may be available under the brand name Duphaston. Patients often find this substance provided by various pharmaceutical manufacturers, where generic versions may exist alongside the primary brand to provide equivalent therapeutic outcomes. These preparations are manufactured to ensure stable release and absorption, allowing for the predictable handling of reproductive health cycles.

Primary Therapeutic Applications

  • Endometriosis management: This substance addresses the symptoms associated with the abnormal growth of tissue outside the uterus.
  • Infertility support: It is utilized to support the secretory transformation of the endometrium, which assists in the early stages of pregnancy maintenance.
  • Dysmenorrhea: The compound is used to alleviate pain associated with menstruation by modulating uterine contractions.
  • Irregular cycle patterns: It helps normalize occurrences of irregular menstrual bleeding or infrequent periods.
  • Luteal phase support: Physicians use this compound during assisted reproductive procedures to ensure the hormonal environment is conducive to pregnancy.

Mechanisms of Hormonal Modulation

Interacting directly with progesterone receptors, dydrogesterone facilitates the development of the uterine lining into a receptive state. Unlike naturally occurring progesterone that might exhibit varying effects depending on the route of administration, this synthetic version is highly stable when taken orally. It effectively signals the body to maintain the endometrial integrity, thereby stabilizing the reproductive hormonal environment. By selectively binding to these receptors without causing significant androgenic or estrogenic side effects, it provides a focused approach to managing symptoms.

Safety Profile

Common Reactions

Patients may occasionally notice transient patterns such as mild headaches, nausea, or localized feelings of abdominal fullness. These signs are generally manageable and often resolve as the body adjusts to the administration of the substance.

Serious Reactions

Immediate medical assessment is necessary if an individual experiences signs of severe allergic reactions (such as skin rashes or breathing difficulties) or symptoms indicative of vascular disturbances, including unexplained swelling or pain in the extremities.

Contraindications

Individuals with a documented history of severe liver dysfunction or specific types of hormone-sensitive growths should avoid this compound. Furthermore, those who experience unexplained vaginal bleeding or known hypersensitivity to the ingredients should opt for alternative therapies.

Interaction Awareness

Alcohol can influence the metabolic processing of hormonal agents, potentially altering the predictability of the therapy. Additionally, certain anticonvulsants or compounds that increase liver enzyme activity may reduce the efficacy of this substance. Please refer to your specific medication’s insert for a full list of potential interactions.

Dosage and Storage Considerations

Typical treatment duration is highly individualized, ranging from short-term acute usage to longer-term management depending on the underlying reproductive condition. Storage should be maintained in a cool, dry environment, away from direct light to prevent the degradation of the active compound. For detailed usage, dosing, and administration, refer to the specific medication's clinical information.

Terminology Guide

Progestogen
A category of substances that mimic the effects of the natural hormone progesterone on the reproductive system.
Endometrium
The mucous membrane that lines the interior surface of the uterus, which becomes the receptive site for implantation.
Luteal Phase
The latter part of the menstrual cycle, during which the lining of the uterus thickens to prepare for potential pregnancy.

Essential Clinical Disclosure

This overview provides purely educational information regarding dydrogesterone and does not constitute medical, diagnostic, or therapeutic advice. Because individual formulations such as Duphaston vary significantly in concentrations, delivery mechanisms, and specific patient requirements, the details provided here should not replace clinical judgment. We disclaim all liability for any medical decisions made based on this text. Always consult your medication’s unique insert and speak with a licensed healthcare professional for guidance tailored to your health.

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