Harvoni
Ledipasvir and sofosbuvir 90/400mg tablets, sold as Harvoni, treat chronic hepatitis C: one tablet daily, taken for 8 to 24 weeks, in 28- or 56-tablet packs.
All strengths and pack prices
| Strength | Pack | Price | Per tablet |
|---|---|---|---|
| 90/400mg | 28 tablets | $306.04 | $10.93 |
| 90/400mg | 56 tablets | $480.48 | $8.58 |
- Category
- Antivirals
- Active ingredient
- Ledipasvir · Sofosbuvir
- Route
- Oral
- Form
- Tablet
- Strengths
- 90/400mg
You will receive a quality generic equivalent, depending on stock.
Shipped in a discreet, unmarked envelope.
Details
- Conditions
- Chronic Hepatitis C
- Brands with the same ingredient
- Ledipasvir/Sofosbuvir
- Therapeutic Class
- Antiviral
- Pharmacological Class
- Polymerase inhibitor
- Minor Side Effects
- Fatigue, Headache
- Moderate Side Effects
- Insomnia
- Dosage Forms
- Tablet
- Administration Route
- Oral
- Originator
- Gilead Sciences
- Duration
- Ongoing
- Storage Instructions
- Store cool.
- Drug Interactions
- Amiodarone
What you will receive
Harvoni is the originator brand name, made by Gilead Sciences. We use it to identify the medicine; the pack you receive is a generic equivalent, not the original Harvoni.
- The same active ingredient (Ledipasvir / Sofosbuvir) at the same strength.
- The exact brand supplied depends on what is in stock when your order ships.
FAQ
Which Harvoni strengths and pack sizes can I order?
Harvoni tablets come in 90/400mg. Packs are 28 or 56 tablets. The pack contains generic ledipasvir + sofosbuvir, not the original Harvoni. Larger packs cost less per tablet.
How is Harvoni delivered to Hong Kong?
Harvoni can be sent by tracked courier in 5 to 9 business days with online tracking, or by standard airmail in 14 to 21 business days, up to 30, without tracking. Very large orders over 120 units may be split into several parcels.
How long does Harvoni take to work?
The virus falls steadily across the course rather than overnight: treatment runs 8 to 24 weeks, and by the last tablet the aim is for the virus to be undetectable in the blood. Blood tests during treatment and a follow-up test afterwards show how it is going.
What time of day should I take Harvoni?
Any time you can keep to. The tablet is taken once every 24 hours and food makes no difference to it, so morning, evening or bedtime all work. What counts is taking it at roughly the same point each day.
Which hepatitis C genotypes does Harvoni treat?
It treats more than one genotype of the hepatitis C virus. A genotype test done beforehand decides how long the course runs and whether ribavirin is added as well. Other genotypes are handled with different antiviral combinations.
Where should I keep my Harvoni tablets?
In the pack they arrived in, somewhere dry and not warm — a bedroom drawer or cupboard suits better than a kitchen shelf near the hob. Heat and damp can affect tablets over months, so keep the current pack closed and open the next only when you need it.
About Harvoni
What Harvoni treats
Harvoni is a hepatitis C treatment that puts two antivirals in one tablet: ledipasvir 90mg and sofosbuvir 400mg. It is used for chronic hepatitis C, a liver infection that can stay active for years and slowly damage the organ, either on its own or with ribavirin. Sofosbuvir blocks the enzyme the virus relies on to copy its genetic material; ledipasvir stops it passing from one liver cell to the next. Between them they push the amount of virus in the blood down, and the aim of a course is for it to become undetectable. Courses run 8 to 24 weeks, shaped by the genotype of the virus and how treatment goes.
How the tablets are taken
Swallow one tablet a day, whole, at a time that suits your routine; a meal is optional. Pick a slot you already keep, such as after brushing your teeth, because a skipped day does more harm than a dose that drifts by an hour. The virus is still present in the early weeks even if you feel perfectly well, so the pack is finished rather than stopped when you feel better. A tablet remembered the same day can be taken then, unless the next one is only hours away. Never double up.
Antacids, heartburn remedies and other drugs
Indigestion medicines made with aluminium or magnesium reduce how much of the tablet gets through, so space them four hours either side of the antiviral dose. Famotidine-type heartburn drugs are easier: 12 hours apart from Harvoni, or both at the same time. St John's wort, a herbal remedy, and amiodarone, used for an irregular heartbeat, also interact.
Side effects to expect
Headache, tiredness, nausea, diarrhoea and poor sleep are the usual complaints, and most fade within a few weeks. Swelling of the lips, mouth or throat, or a rash that keeps spreading, is an allergic reaction and needs urgent treatment.
Hepatitis B deserves its own mention. Anyone who has ever carried that virus, even without symptoms, can see it flare during the course or in the months afterwards. Yellow eyes or skin, dark urine, pale stools, loss of appetite or exhaustion that arrives after starting the tablets need urgent medical care.
Packs and ordering
This is the generic version of the combination: 90/400mg tablets in packs of 28 or 56. A 28-tablet pack is four weeks; a 56-tablet pack is eight. Match the pack to the course length so the tablets do not run out before the end.
Sources
- Ledipasvir and Sofosbuvir: MedlinePlus Drug Information — National Library of Medicine
- Sofosbuvir: MedlinePlus Drug Information — MedlinePlus / National Library of Medicine