Roflumilast
Roflumilast 500mcg tablets, taken once a day to reduce flare-ups in severe COPD with chronic bronchitis, supplied in packs of 30 to 180.
All strengths and pack prices
| Strength | Pack | Price | Per tablet |
|---|---|---|---|
| 500mcg | 30 tablets | $58.50 | $1.95 |
| 500mcg | 60 tablets | $93.60 | $1.56 |
| 500mcg | 90 tablets | $120.60 | $1.34 |
| 500mcg | 120 tablets | $140.40 | $1.17 |
| 500mcg | 180 tablets | $187.20 | $1.04 |
- Category
- Respiratory Health
- Active ingredient
- Roflumilast
- Route
- Oral
- Form
- Tablet
- Strengths
- 500mcg
You will receive a quality generic, depending on stock.
Shipped in a discreet, unmarked envelope.
Details
- Conditions
- COPD
- Therapeutic Class
- PDE4 inhibitor
- Pharmacological Class
- Anti-inflammatory
- Minor Side Effects
- Weight loss, Diarrhoea, Nausea
- Moderate Side Effects
- Headache, Back pain, Insomnia
- Dosage Forms
- Tablet
- Administration Route
- Oral
- Originator
- AstraZeneca
- Onset Time
- Days to weeks
- Duration
- 24 hours
- Storage Instructions
- Store at room temperature.
- Drug Interactions
- CYP3A4 inhibitors
- Age Restrictions
- Adults only
What you will receive
Roflumilast is a generic medicine sold under the name of its active ingredient, Roflumilast.
- The manufacturer depends on what is in stock when your order ships.
- It contains the same active ingredient, at the same strength, as the brand-name versions.
FAQ
What pack sizes of Roflumilast can I order?
Roflumilast tablets are listed in packs of 30 to 180.
Is Roflumilast sent discreetly to Hong Kong?
Every Roflumilast order ships in plain, unbranded packaging with nothing on the outside about the contents. Support answers 24/7 in English and Cantonese by live chat. Order tracking is on the tracking page.
What are the other names for roflumilast?
Brand names for roflumilast include Daliresp and Daxas. Roflumilast tablets are a pure generic roflumilast product and are not any of those brands.
Is roflumilast a steroid?
No. Roflumilast is a PDE4 inhibitor, a different class of medicine, and it is swallowed as a tablet rather than inhaled. Steroid inhalers work directly on the airways; this tablet reduces the inflammation that keeps returning in chronic bronchitis.
Can roflumilast be used for asthma or a sudden attack of breathlessness?
Roflumilast is used for severe COPD with chronic bronchitis, not asthma, and it cannot ease an attack that is already under way. A reliever inhaler is what treats sudden breathlessness; roflumilast is the daily tablet that aims to make those attacks less frequent.
How long does roflumilast take to work?
Expect fewer flare-ups over months rather than a change in the first week. The tablet works on airway inflammation gradually, so a few days tells you little, and the effect depends on taking it every day, good days included.
Does roflumilast cause weight loss?
Yes. Weight loss is one of the more common effects of roflumilast and a frequent reason people stop taking it. A falling appetite often goes with it. Because the change can be gradual, keeping an eye on your weight is worthwhile while you are on the tablets.
Does roflumilast replace my inhalers?
No. Roflumilast is taken as well as your inhalers, not instead of them. Inhalers deliver treatment straight to the lungs, while the tablet is swallowed and works through the bloodstream, so the two are doing different jobs.
About Roflumilast
What roflumilast tablets do for severe COPD
Roflumilast is a tablet for people whose COPD (chronic obstructive pulmonary disease) is severe, who have chronic bronchitis, and who have had flare-ups before. It is taken to cut down how often those flare-ups happen — the spells when a cough, wheeze or breathlessness gets suddenly worse and stays worse for days. The tablet is 500 micrograms (500mcg), the strength used for ongoing treatment.
Is roflumilast a reliever?
No. Roflumilast is a phosphodiesterase-4 (PDE4) inhibitor, which means it damps down inflammation in the airways over weeks rather than opening them within minutes. It is not a bronchodilator, so it will not help a sudden attack of breathlessness — that is what a reliever inhaler is for. What it does instead is lower the background level of inflammation so flare-ups come less often.
Fitting one tablet into the day
Roflumilast is a once-daily tablet, and it does not matter whether you take it with food or between meals. What does help is attaching it to something that already happens at the same point each morning — breakfast, or the same slot as your inhalers. A day's tablet that has been forgotten can still be taken later the same day; two doses are never taken together.
Side effects to expect, and the serious ones
Diarrhoea, nausea, headache, dizziness, back pain, muscle spasm, a drop in appetite and trouble sleeping are the effects reported most often. Roflumilast can also cause weight loss, and weight is usually watched during treatment. New or worsening low mood, anxiety, sleeplessness or thoughts of harming yourself have been reported; these are serious effects and among the reasons people stop taking it. Swelling of the face, lips or throat, or sudden trouble breathing, needs emergency care.
What else affects roflumilast
Rifampicin, carbamazepine, phenytoin and phenobarbital make roflumilast work less well. Ketoconazole, erythromycin, fluvoxamine, enoxacin and cimetidine raise the amount in the body and make side effects more likely. Moderate to severe liver impairment is a reason not to take it. The tablets keep best in their original packaging, away from heat sources and damp.
Sources
- Roflumilast: MedlinePlus Drug Information — MedlinePlus / U.S. National Library of Medicine
- DailyMed - ROFLUMILAST tablet — DailyMed / U.S. National Library of Medicine