Triumeq
Abacavir · Dolutegravir · Lamivudine
Triumeq 600/50/300mg tablets combine abacavir, dolutegravir and lamivudine in one daily HIV treatment, sold in packs of 30, 60 and 90 tablets.
All strengths and pack prices
| Strength | Pack | Price | Per tablet |
|---|---|---|---|
| 600/50/300mg | 30 tablets | $306.00 | $10.20 |
| 600/50/300mg | 60 tablets | $535.20 | $8.92 |
| 600/50/300mg | 90 tablets | $782.10 | $8.69 |
- Category
- HIV Management
- Active ingredient
- Abacavir · Dolutegravir · Lamivudine
- Route
- Oral
- Form
- Tablet
- Strengths
- 600/50/300mg
You will receive a quality generic equivalent, depending on stock.
Shipped in a discreet, unmarked envelope.
Details
- Conditions
- HIV infection
- Therapeutic Class
- Antiretroviral Combination
- Pharmacological Class
- NRTI / Integrase Inhibitor
- Minor Side Effects
- Nausea, headache, fatigue
- Moderate Side Effects
- Insomnia, diarrhoea, rash
- Dosage Forms
- Tablet
- Administration Route
- Oral
- Originator
- ViiV Healthcare
- Onset Time
- 1–3 hours
- Duration
- 24 hours
- Storage Instructions
- Store in the original container.
- Drug Interactions
- Metformin, Antacids, Iron supplements
- Age Restrictions
- Not recommended for small children.
What you will receive
Triumeq is the originator brand name, made by ViiV Healthcare. We use it to identify the medicine; the pack you receive is a generic equivalent, not the original Triumeq.
- The same active ingredient (Abacavir / Dolutegravir / Lamivudine) at the same strength.
- The exact brand supplied depends on what is in stock when your order ships.
FAQ
Which Triumeq strengths and pack sizes can I order?
One strength is sold, 600/50/300mg, in packs of 30, 60 or 90, so a 90 pack covers about three months at one tablet a day. The tablets are generic abacavir with dolutegravir and lamivudine rather than the original Triumeq, and the price per tablet drops as the pack gets bigger.
How can I pay for Triumeq?
Cards (Visa, Mastercard, American Express) go through a secure, encrypted payment page, and Bitcoin or Ethereum are accepted as well; the shop never sees your card details. Changed your mind? An order can be cancelled within 24 hours if it has not been dispatched, and live chat in English or Cantonese is open around the clock.
Can I take Triumeq with antacids or mineral supplements?
Space them out. Aluminium, magnesium and calcium bind dolutegravir in the gut, so antacids, laxatives, multivitamins and mineral supplements with those metals go at least six hours before Triumeq or two hours after it. With a meal, they can be taken at the same time.
What does 600/50/300mg mean on a Triumeq tablet?
Read it left to right as abacavir 600mg, dolutegravir 50mg, lamivudine 300mg. All three sit inside one film-coated tablet, so a single swallow delivers the full adult regimen and nothing else has to be taken for HIV.
Can I stop Triumeq once my viral load is undetectable?
No, not on the strength of a test result. An undetectable load is the effect of the tablets, and the virus is still in the body; once treatment stops it multiplies again and can learn to resist these three drugs. Triumeq is taken long term.
Can I take other HIV medicines with Triumeq?
Triumeq is already a complete regimen — abacavir, dolutegravir and lamivudine are the three HIV drugs in it, so no other HIV tablet is needed alongside. Some people are given a fourth drug when resistance testing shows one of the three ingredients is not working for them.
About Triumeq
One tablet instead of three
HIV is treated with a combination of drugs rather than a single one: the virus mutates quickly and would soon escape a lone medicine. Triumeq does the combining in one film-coated tablet — abacavir 600mg, dolutegravir 50mg and lamivudine 300mg. It is a complete regimen in itself, so there is no second or third HIV tablet to fit into the day. Swallow it whole, once daily; food makes no difference, and a regular slot keeps levels in the blood steady. Packs hold 30, 60 or 90 tablets.
What each ingredient does
Abacavir and lamivudine are nucleoside reverse transcriptase inhibitors. They block reverse transcriptase, the enzyme HIV uses to make a DNA copy of its genetic material after it gets inside a cell. Dolutegravir is an integrase inhibitor and stops the step after that, when the copy is slotted into the cell's own DNA. Two stages blocked at once leaves the virus few ways to survive. HIV is never cleared from the body, so this is not a cure: the aim is to hold the amount of virus in the blood very low, letting the immune system rebuild and hold off the infections that mark AIDS. It works only while it is taken.
Side effects: the common ones, and the one that matters
Nausea, headache, tiredness and difficulty sleeping are reported most often, usually in the first few weeks, and they tend to ease. Diarrhoea and a washed-out feeling also happen.
Abacavir carries a risk the other two ingredients do not: an allergic reaction that can be life-threatening. A mix of fever, rash, stomach pain, nausea, vomiting or diarrhoea, aches, extreme tiredness, or breathing problems, cough and sore throat needs urgent medical care. People who carry a gene called HLA-B*5701 are far more likely to react, so a blood test for it comes before the first tablet. Rarely, abacavir and lamivudine cause a build-up of lactic acid, with fast deep breathing, drowsiness and stomach pain.
Antacids, supplements and other medicines
Dolutegravir sticks to aluminium, magnesium and calcium, which cuts how much of the tablet is absorbed. Antacids, laxatives, multivitamins, mineral supplements and buffered medicines containing those metals belong at least six hours before or two hours after Triumeq. Iron tablets, calcium supplements and sucralfate behave in the same way. St John's wort is the herbal one to leave out, as it lowers dolutegravir levels. Keep the tablets in their packaging in a cool, dry place, and check the date on the pack before starting a new one.
Sources
- Abacavir: MedlinePlus Drug Information — National Library of Medicine
- Dolutegravir: MedlinePlus Drug Information — National Library of Medicine