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Allopurinol tablets lower uric acid to prevent gout attacks and uric acid kidney stones, with plain 300mg tablets and generic Zyloprim in 100mg and 300mg on offer.
Allopurinol
300mg
Allopurinol 300mg tablets cut the body's uric acid production to prevent gout attacks and uric acid kidney stones; packs hold 30, 60 or 90 tablets.
Gout keeps coming back because uric acid stays high between attacks, and allopurinol works on that level, not on the pain of one flare. Uric acid is a waste product. As needle-shaped crystals in a joint it causes an attack; in the urinary tract it forms stones. Allopurinol slows xanthine oxidase, the enzyme that finishes its production, so the body makes less. Once levels stay low, the crystals already in the joint slowly dissolve. That is why it is a daily tablet and not a painkiller.
Most people start allopurinol after a second or third gout attack, to stop more arriving. It also helps stop repeat kidney stones made of uric acid, and it is given during chemotherapy, when breaking-down cancer cells release a surge of uric acid.
Allopurinol is usually one tablet a day, sometimes split into two doses, and after food if it upsets your stomach. The dose starts low and goes up over several weeks. For the first few months attacks may become more frequent before they become rarer, and colchicine is often taken alongside to cover that period. Progress is measured in months.
Aim to drink about two litres a day, spread out, to keep uric acid dilute in the kidneys. If you miss a dose, take it as soon as you think of it, but skip it if the next tablet is nearly due; never take two together. Keep the tablets in their original pack.
Both listings hold the same active ingredient, so the choice comes down to strength and branding. Allopurinol is the plain 300mg tablet. Zyloprim is the brand-name version and comes in 100mg as well as 300mg, which suits a low starting dose or a slow step-up.
Most people notice little. Nausea, loose stools and drowsiness are the usual ones, and it is worth seeing how drowsy you get before you drive. A rash is the one to act on. Itching, hives or spots can be the start of a severe skin reaction, with blistering or peeling, fever, swollen glands, blood in the urine or yellow skin. If a rash like that appears, stop the tablets and get urgent help the same day.
If you are on azathioprine or mercaptopurine (used after transplants and in some immune conditions), your dose of those is lowered when allopurinol is added, because allopurinol blocks the enzyme that clears them. Warfarin lingers in the body for the same reason. Heavy drinking raises uric acid and works against the tablets.
Yes, Allopurinol can be ordered online from PockDose with delivery to Hong Kong. The range is Allopurinol tablets in 300mg and generic Zyloprim in 100mg and 300mg tablets. If a parcel does not arrive within the delivery window or arrives damaged, it is sent again free, or the order is refunded if that is not possible.
Each of the two allopurinol products has its own price per pack, shown on its page in HKD or your selected currency; larger packs usually cost less per unit.
PockDose does not ask you to upload a prescription when you order allopurinol. See the ordering FAQ for details.
Zyloprim is a brand name of allopurinol, which is also sold as Milurit, Zyloric and Purinol. Here, allopurinol can be bought online as generic Zyloprim and allopurinol tablets. These are generics, not the original brand.
Attacks usually become rarer after a few months. Uric acid in the blood falls sooner, often within two weeks, but crystals already in the joints take much longer to dissolve, and nothing speeds that up.
Yes, if you already take it, keep going through the flare; stopping and restarting makes uric acid swing up and down. If you have not started yet, treatment usually waits until the attack has settled, because the first weeks can bring more flares. Allopurinol does not ease the pain of a joint that is already sore.
Same medicine, different brand. Zyloprim comes as 100mg and 300mg tablets, while the plain allopurinol listing is 300mg only — the brand version gives you a lower strength if that is what the start of treatment calls for.
Alcohol works against the tablets in two ways: it nudges uric acid up, and a session of heavy drinking leaves you dehydrated, which makes crystals more likely to form. Beer is the drink most often tied to attacks. Cutting back — or swapping every other drink for water — helps.
A tablet after a meal is easier on the stomach if allopurinol leaves you feeling sick, but food is not required. Consistency counts for more than the exact hour — pick a slot you will remember, morning or evening, and stay with it.