Allopurinol
Allopurinol

0.76
Allopurinol is a medication used to lower high uric acid levels to prevent gout attacks and the formation of kidney stones.


Ingredient
Availability
In Stock
Delivery
Airmail (14-21 days) | EMS trackable (5-9 days)
Product is shipped in a fully discreet envelope with no content disclosure, including all required documentation inside

Product Sheet

Active Ingredient(s)
Allopurinol
Reference Brand
Allopurinol
Product Origin
Generic Product
Reference Manufacturer
GlaxoSmithKline
Product Form
Tablet
Regulatory Classification
Rx
Primary Category
Pain Management
Product Category
Xanthine Oxidase Inhibitor
Pharmacological Class
Antigout agent
Clinical Indications
Gout, Kidney stones, Elevated uric acid
Manufacturer Description
Allopurinol is a medication used to lower high uric acid levels to prevent gout attacks and the formation of kidney stones.
Mechanism of Action
Allopurinol reduces the production of uric acid in the body by inhibiting the xanthine oxidase enzyme.
Route of Administration
Oral
Onset Time
2–6 hours
Duration
18–30 hours
Contraindications
Hypersensitivity
Severe Adverse Events
Severe skin reaction, Liver toxicity
Common Side Effects
Drowsiness, Upset stomach
Uncommon Side Effects
Skin rash, Diarrhea
Drug Interactions
Azathioprine, Mercaptopurine, Warfarin
Pregnancy Safety Warnings
Consult a physician regarding use.
Age Restrictions
Monitor in pediatric patients
Storage Guidelines
Keep at room temperature.
Related Products
Febuxostat, Colchicine

Allopurinol FAQ

Is Generic Allopurinol bioequivalent?

The generic formulation meets established pharmaceutical standards for bioequivalence to the reference product, ensuring identical pharmacokinetic properties.

How do multi-source economics impact cost?

The introduction of equivalent formulations fosters a competitive environment, which often facilitates more localized supply-side economics.

How is the affiliate logistics process managed?

Logistical routing coordinates with WHO-GMP compliant facilities to ensure product handling follows established safety and quality regulations.

Does formulation variance affect efficacy?

Standardized active pharmaceutical ingredients ensure that biological action remains consistent regardless of the specific manufacturing source.

What impacts chemical stability?

Exposure to moisture, light, and fluctuating temperatures degrades the product, requiring strict adherence to storage instructions to maintain quality.

What are the import regulations for Hong Kong?

Personal imports of pharmaceutical substances must comply with all local Pharmacy and Poisons Board regulations to facilitate entry into the territory.

Does this medication appear on drug tests?

The administration of this compound does not relate to prohibited substances typically screened in high-stakes testing, yet no universal guarantees exist regarding specific panel sensitivities.

Clinical Identity of Allopurinol

Allopurinol functions as a xanthine oxidase inhibitor available in 300mg tablets. This generic formulation provides a standardized pharmaceutical preparation for the clinical management of hyperuricemia-elevated levels of uric acid in the blood.

Cellular Pharmacodynamics

Allopurinol decreases the endogenous production of uric acid by inhibiting the xanthine oxidase enzyme. This enzyme facilitates the biochemical conversion of hypoxanthine to xanthine and subsequently to uric acid. By lowering urate concentration, the compound prevents the crystallization of uric acid within synovial spaces and tissues.

Regulatory Indications

Approved by the Pharmacy and Poisons Board (PPB) of Hong Kong, this therapeutic option manages conditions characterized by excessive urate accumulation. Indications include primary and secondary gout, recurrent uric acid stone formation, and urate nephropathy-kidney damage related to high uric acid levels. Clinical use focuses on the long-term reduction of serum urate rather than acute inflammatory cessation.

Pregnancy and Developmental Risks

Consult a physician immediately regarding the use of this compound during pregnancy or lactation. Limited data exists concerning fetal safety and potential physiological impacts, necessitating a formal professional risk-benefit analysis before initiation.

Renal Contraindications

Severe impairment of renal function necessitates rigorous dose modification or complete avoidance. Monitor baseline and ongoing laboratory metrics to prevent accumulation of oxypurinol-a primary active metabolite.

Hypersensitivity Risks

Discontinue usage immediately upon the manifestation of skin rashes or allergic reactions. Genetic screening for specific HLA-B*58:01 alleles may identify individuals at elevated risk for hypersensitivity syndromes.

Common Adverse Events

Patients may report mild gastrointestinal discomfort, including nausea or abdominal shifts. Routine hematological monitoring detects transient changes in blood cell counts during early treatment phases.

Serious Adverse Events

Systemic hypersensitivity reactions-including exfoliative dermatitis or organ-specific inflammatory responses-require immediate discontinuation. Bone marrow suppression remains a rare but significant clinical event requiring medical supervision.

Pharmacological Interactions

Concomitant administration with azathioprine or mercaptopurine elevates plasma concentrations significantly. Metabolic pathways overlap, increasing the risk of toxicity when combined without physician-led dose adjustment.

Administration Method

Administered orally via tablets. Swallow the pill whole with liquid. All frequency and daily total decisions belong exclusively to a primary care physician.

Storage and Handling

Store at room temperature in a dry, dark environment. Keep away from humidity to maintain the integrity of the chemical structure. Return unused medication to local pharmacies or designated chemical waste collection points in Hong Kong for disposal.

Medical and Access Disclaimer

This content provides information only and does not replace medical advice, diagnosis, or treatment. Always consult a licensed healthcare provider in Hong Kong before altering any therapy. This service coordinates international logistical routing through regulated, WHO-GMP compliant pharmacies for users with prior physician authorization. We recommend checking local subsidized options under the Hong Kong national health framework first. This affiliate network acts strictly as a secondary resource. Licensed professionals in regulated jurisdictions perform all dispensing and medical reviews to support the continuity of care established by your doctor.

Glossary

Hyperuricemia
A clinical state defined by higher-than-normal concentrations of uric acid in the human blood serum.
Xanthine Oxidase
An enzyme responsible for the metabolic pathway that converts purines into uric acid within the liver.
Urate Nephropathy
A condition where excessive accumulation of uric acid crystals causes functional damage to kidney tissues.
Bioequivalence
The property where a generic formulation demonstrates the same rate and extent of absorption as the originator product.
Categories