Colchicine

Colchicine is an anti-inflammatory tablet used to treat gout flares and familial Mediterranean fever, sold on PockDose as 0.5mg tablets under the Colchicine and Colcrys names.

Colchicine

Colchicine

0.5mg

Colchicine 0.5mg tablets, used for gout attacks and familial Mediterranean fever, offered in packs from 60 tablets upwards, with the brand-name Colcrys at the same strength.

from $0.37 / tablet View

Colcrys

Colchicine

0.5mg

Colcrys is the brand name for colchicine 0.5mg tablets, used to treat gout flares and familial Mediterranean fever and sold here as generic colchicine.

from $0.41 / tablet View

What colchicine is used for

Colchicine is an anti-inflammatory medicine that comes from the autumn crocus, and it is still the tablet many people reach for when a gout attack starts. Gout is a form of arthritis caused by needle-shaped uric acid crystals settling into a joint, most often the big toe, usually in the middle of the night. The joint turns hot, swollen and very painful. Colchicine shortens that reaction and takes the edge off it. It is also used for familial Mediterranean fever, an inherited condition that brings repeated bouts of fever and inflammation, and for pericarditis, inflammation of the sac around the heart.

How colchicine works and how a flare is treated

This is not a painkiller that blunts the pain within the hour. Colchicine slips inside white blood cells and blocks the tiny tubes they use to move and multiply, so fewer of them reach the joint and less of the signal that drives swelling gets released. Timing does a lot of the work: started in the first hours of a flare, it has much less inflammation to undo.

A flare is treated with a short course: a starting dose, a smaller one a couple of hours later, then small doses through the next day or two until the pain eases. Between attacks, a low dose such as 0.5mg once or twice a day can keep flares from returning so often. Swallow the tablets whole with water.

Side effects to watch for

Diarrhoea is the one most people meet, sometimes with nausea, vomiting or stomach cramps, and it often turns up when the dose is on the high side. Muscle weakness or aching, tingling or numbness in the fingers and toes, a sore throat or fever, easy bruising or bleeding, and unusual tiredness or paleness are signs that too much colchicine has built up in the body. A rash or thinning hair is reported less often.

Medicines that raise colchicine levels

The liver and kidneys clear colchicine, and a fair number of common medicines slow that process and let the level climb. Among them are the antibiotics clarithromycin and erythromycin, the antifungal ketoconazole, some HIV medicines, the heart medicines verapamil and diltiazem, and ciclosporin. Statins, taken for cholesterol, also slow clearance and carry their own risk of muscle problems. Grapefruit juice has a similar effect.

Colchicine and Colcrys: the two listings

Both products here are 0.5mg tablets of the same ingredient. Colchicine is named after the ingredient itself; Colcrys is a brand name for it. With a single strength and a single form, the choice comes down to the name on the box, and both belong to the shop's painkillers group. Anyone taking a tablet twice a day to hold flares off will get through more packs than someone treating the odd attack.

Sources

  1. Colchicine 500 micrograms Tablets - Patient Information Leaflet (PIL) - (emc) | 6415 — UK Electronic Medicines Compendium (EMC)
  2. Colchicine | Drugs | BNF | NICE — NICE (BNF)
Can I order Colchicine online in Hong Kong?

Colchicine can be ordered online in Hong Kong. The range is Colchicine tablets in 0.5mg and generic Colcrys tablets in 0.5mg. Payment is by Visa, Mastercard or American Express on a secure, encrypted payment page, or in Bitcoin or Ethereum.

How much does Colchicine cost?

Prices vary between the two colchicine products and between pack sizes. Every product page lists its current prices.

Do I need a prescription to order Colchicine?

PockDose does not ask you to upload a prescription when you order colchicine. See the ordering FAQ for details.

What are the other names for colchicine?

Colcrys is a brand name of colchicine, which is also sold as Colgout, Mitigare and Zycolchin. Here, colchicine can be bought online as generic Colcrys and colchicine tablets. These are generics, not the original brand.

How long does colchicine take to work on a gout attack?

It is not a painkiller that works within the hour. A gout attack usually builds to its worst over 12 to 24 hours and then eases over several days. Started in the first hours of a flare, colchicine shortens that, and the joint should feel calmer within a day or two.

Can colchicine be taken every day to prevent gout attacks?

Yes. A low daily dose, often 0.5mg once or twice a day, is taken to reduce how often flares come back, and it is usually continued for several months. A flare course works differently: more tablets over a day or two, stopped once the pain settles.

Is Colcrys the same as colchicine?

Colcrys is a brand name for colchicine, so the active ingredient is the same. Both listings here are 0.5mg tablets, which means the only difference you are choosing between is the name on the pack, not a strength or a form.

Does grapefruit juice affect colchicine?

Grapefruit juice slows the liver enzymes that clear colchicine, so more of the medicine stays in the body than usual. Grapefruit itself does the same. Water is a simpler choice while you are taking a course of tablets.

What does 0.5mg mean on a colchicine tablet?

0.5mg, also written 500 micrograms, is how much colchicine one tablet contains, and it is the only strength sold here. A flare course adds up to several tablets over a day or two, while a preventive routine is usually one or two tablets a day.

What is colchicine called in Hong Kong?

In Hong Kong, colchicine is registered under brand names including Colgout and Colcina. Here, colchicine can be ordered as Colchicine, a generic. In Chinese, colchicine is 秋水仙鹼.