Cyclophosphamide
Cyclophosphamide is an alkylating medicine used in some cancers and severe autoimmune conditions, sold here as Cytoxan 50mg tablets for oral treatment.
What the tablets do
Cyclophosphamide is an alkylating chemotherapy medicine, from the group once called nitrogen mustard. It reaches the body inactive, and the liver turns it into the form that does the work. That active form ties the two strands of a cell's DNA together, so the cell can no longer copy its DNA or divide. Cells that multiply quickly feel this most, which is why the medicine works against cancer and also why hair, bone marrow and the bladder lining are affected. The same action calms an overactive immune system.
What cyclophosphamide treats
Lymphoma and leukaemia are the best-known uses, along with some solid tumours, including breast and ovarian cancer. Among autoimmune conditions it is chosen when the disease is severe or other treatments have not held it back: lupus that has reached the kidneys, vasculitis (inflamed blood vessels), nephrotic syndrome (protein leaking through the kidneys) and rheumatoid arthritis. The shop's oncology range carries the oral form as Cytoxan 50mg tablets.
How a course is run
Treatment comes in cycles, with rest periods between them, and the tablet is usually a single daily dose. Anyone who feels sick after it can take it with a meal. Drinking plenty of water through the day protects the bladder, which is why it is part of the routine. Between cycles blood counts are checked, and what they show decides how the next cycle is planned.
Side effects to expect
Nausea, appetite loss and tiredness often follow a dose, and hair thins or falls out within the first few weeks; it grows back after the course ends. Mouth ulcers and diarrhoea are common too. Because the bone marrow slows, infections take hold more easily and bruises or nosebleeds appear with less cause. Bladder irritation is the effect to act on quickly: blood in the urine, or pain when passing urine, needs urgent attention. Fertility can be affected, sometimes permanently, and years later there is a small added risk of a second cancer.
What interacts with cyclophosphamide
Taking allopurinol for gout alongside it puts extra strain on the bone marrow. Warfarin becomes stronger under cyclophosphamide, which is why bruising and bleeding are watched. Rifampicin, carbamazepine, phenytoin and St John's wort speed up the liver enzymes, and the body then makes less of the active form from each tablet. Live vaccines are avoided while treatment lasts.
Sources
- Cyclophosphamide: MedlinePlus Drug Information — National Library of Medicine
- Cancer - NHS — UK National Health Service (NHS)
Can I order Cyclophosphamide online in Hong Kong?
Cyclophosphamide can be ordered online with delivery to Hong Kong. The range is generic Cytoxan, also sold as Cyclophosphamide tablets, at 50mg. An order can be cancelled within 24 hours if it has not been dispatched, and support answers 24/7 in English and Cantonese.
How are Cyclophosphamide prices shown?
Prices vary between pack sizes. The product page lists its current prices in HKD or in the currency you choose.
Does PockDose sell generic Cytoxan?
Yes, generic Cytoxan is listed as 50mg tablets and contains cyclophosphamide. It is also sold as the plain ingredient version, Cyclophosphamide tablets, also at 50mg in tablet form.
What brand names does cyclophosphamide have?
Cytoxan is a brand name of cyclophosphamide, which is also sold as Endoxan. Here, cyclophosphamide can be bought online as generic Cytoxan. These are generics, not the original brand.
How is a cyclophosphamide dose decided?
Doses are worked out for each person rather than set by the tablet. Body size and the condition being treated both count, so two people taking the same 50mg tablets may take a different number of them a day, and the plan can change from one cycle to the next.
How long does cyclophosphamide treatment last?
It runs in cycles: a stretch of daily doses, then a break while the body recovers, then the next cycle. A course often lasts several months. Some autoimmune conditions are kept steady with a lower daily dose for a year or longer.
Does cyclophosphamide make your hair fall out?
Hair thinning or loss is common, usually showing up in the first few weeks of treatment, and it can affect eyebrows and body hair as well as the scalp. New hair normally starts growing back once the course is finished.
Can cyclophosphamide affect fertility?
Yes — it can reduce fertility in both men and women, and the effect is sometimes permanent. Periods may stop during treatment and sperm production can fall. Whether fertility returns depends on the total dose and how long treatment continues.
Where should I keep cyclophosphamide tablets?
Keep them in their original blister pack or bottle, somewhere cool and out of direct sunlight, and where children cannot reach them. Keep the carton as well; the strength and course details are printed on it.