Domperidone

Domperidone is an anti-sickness medicine for nausea and vomiting, sold here as 10mg tablets under its own name and as the brand Motilium.

Domperidone

Domperidone

10mg

Domperidone 10mg tablets are an anti-sickness medicine for nausea and vomiting, and for the fullness and upper stomach pain that come with slow stomach emptying.

from $0.46 / tablet View

Motilium

Domperidone

10mg

Motilium 10mg tablets contain domperidone for nausea and vomiting, listed here in packs of 30 to 360 tablets as a generic version of the brand.

from $0.46 / tablet View

What domperidone is used for

Domperidone is an anti-sickness medicine, taken to stop nausea and vomiting. It suits the queasy, over-full feeling that lingers when a stomach empties slowly — bloating, early fullness and queasiness after only a small meal. Gastroparesis, a stomach that takes far too long to clear, is one of the conditions it is used for. Treatment is usually short, and the aim is the smallest dose that keeps the sickness away.

How it works

Nausea often starts in the gut rather than the head. Domperidone blocks dopamine, the chemical messenger that normally holds back the muscles of the stomach wall. With that brake released, the muscle at the top of the stomach tightens and the one at the bottom relaxes, so food and fluid travel downwards as they should and the urge to vomit fades.

Taking the tablets

Swallow a tablet with water 15 to 30 minutes before a meal, which is when it does its best work. Up to three doses a day can be taken. After food, domperidone is absorbed more slowly and relief is less reliable. If a dose slips your mind, leave it out and carry on with the next one at its usual time rather than taking two together. Keep the pack somewhere cool and out of direct light.

Side effects and interactions

A dry mouth is the one people notice most, and it tends to ease. Headache, stomach cramps and looser stools are also reported. Domperidone raises prolactin, a hormone that can leave breasts tender or swollen, sometimes with a little milk leakage, and can make periods irregular; these effects usually settle once the course ends. Rarely, it disturbs the rhythm of the heart, which is why the dose is kept low and the course short: palpitations, fainting or a racing, uneven heartbeat need urgent treatment, as do facial or throat swelling and breathing trouble.

Some medicines slow the way the liver clears domperidone and push its level in the blood higher, while others add to the risk of an abnormal heart rhythm. Several antifungals and antibiotics fall into those groups and are not taken alongside it.

The two listings

Both products here are 10mg tablets of the same ingredient: plain Domperidone and Motilium, the brand name for domperidone. They sit in the shop's digestive health range.

Sources

  1. About domperidone - NHS — National Health Service
  2. Domperidone 1mg/ml Oral Suspension - Summary of Product Characteristics (SmPC) - (emc) — electronic medicines compendium (emc) / Zentiva
Where can I order Domperidone for delivery in Hong Kong?

Domperidone can be ordered online with delivery to Hong Kong. The page carries plain Domperidone tablets and generic Motilium, both at 10mg. A parcel that does not arrive within its delivery window, or that arrives damaged, is sent again at no cost, and if that cannot be done the order is refunded.

How are Domperidone prices shown?

Each of the two domperidone products has its own price per pack, shown on its page in HKD or your selected currency; larger packs usually cost less per unit.

Do I need a prescription to order Domperidone?

PockDose does not ask you to upload a prescription when you order domperidone. See the ordering FAQ for details.

What brand names does domperidone have?

Motilium is a brand name of domperidone, which is also sold as Domstal. Here, domperidone can be bought online as generic Motilium and domperidone tablets. These are generics, not the original brand.

How long does domperidone take to work?

Relief usually comes within 30 to 60 minutes of a dose, and it works fastest when the stomach is empty rather than full. There is no build-up period: each tablet does its own job, so a dose taken when you need it counts on its own.

Does domperidone make you sleepy?

Not usually. It acts on the gut and reaches the brain only in tiny amounts, so it is not one of the anti-sickness medicines that leaves people drowsy. Dry mouth, headache and stomach cramps are reported far more often.

Can I take domperidone with antibiotics?

Some, but not all. Clarithromycin and erythromycin are the two antibiotics that should not be combined with domperidone, because they raise the amount of it circulating in the blood. The antifungals ketoconazole and itraconazole are avoided for the same reason.

How long can I take domperidone for?

Usually for a short stretch, around a week for nausea and vomiting. Longer courses exist but are kept for particular situations, and short ones are favoured because of the rare effect on heart rhythm.

Is domperidone an antacid?

No. Antacids neutralise stomach acid. Domperidone does something else: it helps the stomach empty and eases nausea, so it is aimed at fullness, bloating and sickness rather than acid.