Anafranil
Anafranil capsules contain clomipramine, a tricyclic antidepressant used for obsessive-compulsive disorder, in 10mg, 25mg and 50mg strengths, sold in packs of 30 capsules and upwards.
All strengths and pack prices
| Strength | Pack | Price | Per capsule |
|---|---|---|---|
| 10mg | 30 capsules | $34.80 | $1.16 |
| 10mg | 60 capsules | $43.20 | $0.72 |
| 10mg | 90 capsules | $63.00 | $0.70 |
| 10mg | 120 capsules | $78.00 | $0.65 |
| 10mg | 180 capsules | $108.00 | $0.60 |
| 10mg | 360 capsules | $201.60 | $0.56 |
| 25mg | 30 capsules | $37.50 | $1.25 |
| 25mg | 60 capsules | $64.80 | $1.08 |
| 25mg | 90 capsules | $60.30 | $0.67 |
| 25mg | 120 capsules | $117.60 | $0.98 |
| 25mg | 180 capsules | $158.40 | $0.88 |
| 25mg | 360 capsules | $284.40 | $0.79 |
| 50mg | 30 capsules | $45.00 | $1.50 |
| 50mg | 60 capsules | $75.60 | $1.26 |
| 50mg | 90 capsules | $101.70 | $1.13 |
- Category
- Antidepressants
- Active ingredient
- Clomipramine
- Route
- Oral
- Form
- Capsule
- Strengths
- 10/25/50mg
You will receive a quality generic equivalent, depending on stock.
Shipped in a discreet, unmarked envelope.
Details
- Conditions
- Obsessive-compulsive disorder
- Therapeutic Class
- Tricyclic Antidepressant
- Pharmacological Class
- SSRI-like properties
- Minor Side Effects
- Dry mouth, Drowsiness
- Moderate Side Effects
- Tremor, Sweating
- Dosage Forms
- Capsule
- Administration Route
- Oral
- Originator
- Novartis
- Duration
- 24 hours
- Storage Instructions
- Store at room temperature away from light.
- Drug Interactions
- MAO inhibitors, SSRIs
- Age Restrictions
- Use with caution in paediatric patients.
What you will receive
Anafranil is the originator brand name, made by Novartis. We use it to identify the medicine; the pack you receive is a generic equivalent, not the original Anafranil.
- The same active ingredient (Clomipramine) at the same strength.
- The exact brand supplied depends on what is in stock when your order ships.
FAQ
Which Anafranil strengths and pack sizes can I order?
Anafranil capsules come as 10mg, 25mg and 50mg. The 10mg and 25mg strengths are sold in packs of 30 to 360 capsules, while 50mg comes in packs of 30 to 90 capsules. This is generic clomipramine, not the original Anafranil. Larger packs cost less per capsule.
How will Anafranil be delivered to Hong Kong?
For Anafranil, tracked courier takes 5 to 9 business days with online tracking, while standard airmail takes 14 to 21 business days, up to 30, and is untracked. Every order arrives in plain, unbranded packaging. If a parcel does not arrive within the delivery window or arrives damaged, it is sent again free; if that is not possible, you receive a refund.
How long does Anafranil take to work?
Some people sleep and eat better within a week or two, but the obsessional symptoms it is taken for usually take several weeks to shift, and OCD often responds more slowly than depression does. Steady daily dosing matters more than any single dose.
Can I drink alcohol with Anafranil?
Alcohol adds to the drowsiness and dizziness clomipramine already causes, and it can leave you unsteady on your feet, especially in the first weeks and at higher doses. If you do drink, keep it to a minimum while your dose is being adjusted.
What happens if I stop Anafranil suddenly?
Stopping abruptly can bring nausea, headache, sweating, chills and trouble sleeping, and the original symptoms can return quickly. Doses are normally reduced in steps over weeks rather than stopped in one go.
Does Anafranil affect sex?
Delayed orgasm, lower sex drive and trouble getting or keeping an erection are common with tricyclics, and they tend to be worse at higher doses. These effects usually wear off after the medicine is stopped.
What should I do if I miss a dose of Anafranil?
Take it when you remember, as long as several hours remain before your usual next dose. If the next dose is close, wait and take that one only; doubling up brings more side effects, not a faster effect.
About Anafranil
Anafranil capsules and what they treat
Anafranil is the brand name of clomipramine, a tricyclic antidepressant, and the capsules are bought mostly for obsessive-compulsive disorder (OCD): thoughts that return uninvited, and the checking, counting or washing that builds up around them. The same capsules are used for depression, particularly when a sedating drug is wanted, and in adults as an add-on for cataplexy, the sudden muscle weakness that comes with narcolepsy.
How clomipramine works, and why it takes weeks
Clomipramine slows the re-uptake of serotonin and noradrenaline, two messengers nerve cells use to signal each other. More of both stays in the gap between cells, which gradually changes the circuits behind mood and the urge to repeat an action. It also blocks histamine and acetylcholine receptors, which is why a dry mouth, drowsiness and constipation are so typical of it. Low mood often lifts before obsessional symptoms do.
Taking your capsules
Swallow them whole with water. Treatment usually starts on a low strength such as the 10mg capsule and is stepped up slowly, so the 25mg and 50mg capsules suit people who have settled on a higher amount. Some take the whole day's dose at bedtime and some split it; clomipramine is one of the more sedating tricyclics, so an evening dose suits many people. Keep to the same times each day, and leave the capsules in their blister somewhere cool and dry.
Side effects and what not to mix
Dry mouth, constipation, blurred vision, sweating, dizziness, drowsiness, weight gain and shaky hands are the usual complaints, and most ease within a few weeks. An irregular heartbeat, fainting or a seizure needs urgent treatment, as does agitation with fever and muscle twitching. Alcohol and other sedating medicines sharpen the drowsiness. Clomipramine is never taken with an MAOI antidepressant, and at least two weeks separate the two. Some antifungal and heart-rhythm medicines push its level in the body up.
Capsules or tablets?
This listing is the capsule form, 10mg, 25mg and 50mg. Clomipramine is also stocked here as Clomipramine tablets, same three strengths, with depression among its uses. Pick the form you already know; both contain the same ingredient.
Sources
- Clomipramine: MedlinePlus Drug Information — National Library of Medicine
- Clomipramine 10 mg Capsules, Hard - Summary of Product Characteristics (SmPC) - (emc) — UK Electronic Medicines Compendium (EMC)