Avanafil
Avanafil

2.83
Avanafil is a fast-acting oral medication indicated for the clinical management of erectile dysfunction in adult men.


Ingredient
Availability
In Stock
Delivery
Airmail (14-21 days) | EMS trackable (5-9 days)
Product is shipped in a fully discreet envelope with no content disclosure, including all required documentation inside

Product Sheet

Active Ingredient(s)
Avanafil
Reference Brand
Spedra
Product Origin
Generic Product
Reference Manufacturer
Mitsubishi Tanabe
Product Form
Tablet
Regulatory Classification
Rx
Primary Category
Erectile Dysfunction
Product Category
PDE5 inhibitor
Pharmacological Class
Vasodilator
Clinical Indications
Erectile dysfunction
Manufacturer Description
Avanafil is a fast-acting oral medication indicated for the clinical management of erectile dysfunction in adult men.
Mechanism of Action
Avanafil is a highly selective PDE5 inhibitor that relaxes vascular smooth muscles, increasing blood flow to the reproductive organs during sexual arousal.
Route of Administration
Oral
Onset Time
15–30 minutes
Duration
6 hours
Contraindications
Nitrate medication use, Severe heart disease
Severe Adverse Events
Priapism, Vision changes
Common Side Effects
Headache, Flushing
Uncommon Side Effects
Nasal congestion, Back pain
Drug Interactions
Nitrates, Alpha blockers
Pregnancy Safety Warnings
Not applicable.
Storage Guidelines
Keep cool and dry.
Related Products
Sildenafil, Tadalafil

Avanafil FAQ

Can avanafil be taken with alcohol?

Moderate alcohol consumption does not generally affect avanafil’s effectiveness, but excessive drinking can lower blood pressure and reduce erection quality. Patients should limit alcohol intake to avoid dizziness or hypotension.

How long before sex should I take avanafil?

Avanafil can be taken as early as 15 minutes before anticipated sexual activity. Peak effects are usually observed within 30-60 minutes.

What should I do if I miss a dose?

If sexual activity does not occur, discard the tablet. Do not take another dose later the same day, as avanafil is intended for single-dose use per 24-hour period.

Are there any dietary restrictions with avanafil?

A high-fat meal may delay onset slightly, but no strict dietary restrictions exist. It is advisable to avoid large amounts of fatty foods immediately before taking the pill if rapid onset is desired.

Will avanaft work if I have high blood pressure?

Avanafil can be used in men with controlled hypertension. Uncontrolled severe hypertension is a relative contraindication, and blood pressure should be assessed before starting therapy.

Can I take avanafil if I am on an alpha-blocker for prostate enlargement?

Yes, but a lower starting dose (50 mg) is recommended and blood pressure should be monitored, as the combination can cause additive hypotensive effects.

Is avanafil safe for men with diabetes?

Men with diabetes may benefit from avanafil, but they should ensure good glycemic control and discuss any peripheral vascular disease with their physician, as these conditions can impact erectile function.

What is the difference between avanafil and other PDE5 inhibitors?

Avanafil has a faster onset (as early as 15 minutes) and higher selectivity for the PDE5 enzyme, which may result in fewer off-target side effects compared with older agents. Clinical effectiveness and safety profiles are comparable when used appropriately.

How should I store avanafil to maintain its potency?

Keep the tablets at room temperature, away from moisture, heat, and direct sunlight. Ensure the bottle is tightly closed and stored out of reach of children.

Primary Chemical Characteristics of Avanafil

Avanafil belongs to a specific class of compounds known as phosphodiesterase type 5 (PDE5) inhibitors. This chemical structure is primarily utilized to address concerns related to erectile dysfunction. By affecting certain pathways within the circulatory system, this substance assists in the physical response required during sexual stimulation.

As a therapeutic agent, it is recognized for its relatively rapid onset of action compared to other substances within the same class. The compound works by targeting specific enzymes that regulate blood flow, which helps support the maintenance of an erection. It does not carry hormonal or aphrodisiac properties; rather, it functions solely by facilitating physiological blood circulation when a person is naturally stimulated.

Physical Formulations and Availability

Avanafil is the active component found in various medicinal formulations. Within the Hong Kong healthcare environment, individuals may encounter this ingredient under specific brand names or as part of a therapeutic regimen determined by a practitioner. These medications are typically supplied as oral tablets, available in varied concentrations to suit individual requirements.

Whether an option is branded or generic, the core functionality of the API remains consistent based on its chemical profile. Each formulation is engineered to ensure stable release and absorption within the digestive system. Patients should note that different brands might employ different non-active ingredients, such as binders or colorants, which are reflected in the specific medication labeling.

Therapeutic Indications

This compound is utilized to address symptoms of erectile dysfunction, a condition characterized by the inability to attain or sustain an erection firm enough for sexual activity. It is prescribed for adult males who experience these physiological barriers regularly.

Clinical usage of the substance focuses on improving physical performance and personal satisfaction. The compound is meant to be used on an as-needed basis rather than as a continuous daily maintenance therapy. By improving the efficiency of local blood vessel dilation, it allows for a more reliable physical response to internal arousal cues.

Mechanism of Action

To function properly, the body relies on specific chemical signals to allow muscles in the blood vessels to relax. When this relaxation occurs, blood flows more easily into the tissue, leading to an erection. During periods of erectile dysfunction, certain enzymes can work against this process, causing restricted flow.

Avanafil functions by temporarily blocking these limiting enzymes. When the body receives signals of sexual arousal, the substance helps the blood vessels remain in a widened state for a longer duration. This facilitates the necessary increase in blood volume to the target area, provided the individual is physically or mentally stimulated. Without such stimulation, the chemical will not produce an automatic or unwanted physical reaction.

Safety and Biological Considerations

Common Reactions

Users may occasionally experience brief warmth or redness of the face and neck, known as flushing. Other common patterns include mild headaches, nasal congestion, or minor upset stomach as the body adjusts to the increased circulation.

Serious Reactions

Individuals should monitor for signs of a prolonged or painful erection lasting longer than four hours, as this requires medical attention. Other concerns include sudden changes in hearing or vision, or signs of an allergic reaction involving skin rashes or difficulty breathing.

Contraindications

This substance should not be combined with medicines containing nitrates or nitric oxide donors, as this mixture can lead to significant and sudden drops in blood pressure. Individuals with severe liver or kidney conditions, or those who have experienced recent cardiac events, are typically advised against this treatment.

Interaction Awareness

Alcohol can temporarily alter blood pressure levels and may affect the efficiency of the medication. Additionally, certain types of antifungal or antibiotic medicines may slow the metabolism of this compound. Always review the specific medication insert for a full list of substances that may interfere with how the API is processed.

Usage Context and Patient Guidance

Storage of these medications should be in a cool, dry environment away from direct sunlight, maintaining the integrity of the tablet. The timing of administration varies according to the specific formulation guidelines provided in the medication’s packaging. For detailed usage, dosing, and administration, refer to the specific medication's clinical information. Treatment duration and expectations should be discussed during evaluation with a healthcare provider to ensure the medication aligns with individual cardiovascular health.

Clinical Nomenclature Glossary

Phosphodiesterase type 5 (PDE5)
An enzyme found in many tissues that regulates blood flow by breaking down messenger chemicals in the body.
Vasodilation
The widening of blood vessels, resulting from the relaxation of smooth muscle cells within the vessel walls.
Generic
A version of a medication that contains the same active compound as a brand-name product while potentially differing in inactive ingredients.

Clinical Disclosure and Safety Overview

This educational overview provides general information regarding Avanafil and does not constitute medical advice or a recommendation for use. Individual medications containing this ingredient differ in strength, formulation, and application instructions. We disclaim all liability for any clinical application or outcomes related to the use of this substance. Please consult the specific labeling of your medication and reach out to a licensed healthcare professional in Hong Kong to discuss your unique health history before starting any new pharmacological regimen.

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