Combimist L Inhaler

Levosalbutamol · Ipratropium bromide

Combimist L Inhaler is a 50/20mcg pressurised inhaler that pairs levosalbutamol with ipratropium bromide for asthma and COPD, sold as one inhaler or in packs of two or three.

All strengths and pack prices
Combimist L Inhaler: price of every strength and pack size
Strength Pack Price
50/20mcg 1 inhaler $30.59
50/20mcg 2 inhalers $51.00
50/20mcg 3 inhalers $68.85
Active ingredient
Levosalbutamol · Ipratropium bromide
Route
Inhalation
Form
Inhaler
Strengths
50/20mcg

Shipped in a discreet, unmarked envelope.

Details

Conditions
Asthma · COPD
Brands with the same ingredient
Levosalbutamol/Ipratropium
Therapeutic Class
Bronchodilator
Pharmacological Class
Beta-agonist, Anticholinergic
Minor Side Effects
Tremor, Dry mouth
Moderate Side Effects
Rapid heart beat
Dosage Forms
Inhaler
Administration Route
Inhalation
Manufacturer
Cipla Ltd
Onset Time
5 minutes
Duration
4-6 hours
Storage Instructions
Do not puncture canister; keep away from heat.
Drug Interactions
Beta blockers
Age Restrictions
Use as directed for age.

FAQ

How many Combimist L Inhalers can I buy?

Combimist L Inhaler comes in 50/20mcg inhalers, sold singly or in packs of 2 or 3. Larger packs cost less per inhaler.

What arrives when I order Combimist L Inhaler to Hong Kong?

Your Combimist L Inhaler arrives in plain, unbranded packaging with nothing on the outside about the contents. Tracked courier takes 5 to 9 business days with online tracking; standard airmail takes 14 to 21 business days and is untracked.

What does 50/20mcg mean on a Combimist L Inhaler?

It is the dose carried in each puff. The first figure, 50mcg, is levosalbutamol; the second, 20mcg, is ipratropium bromide. One press of the canister releases both medicines together, so the strength is written as a pair rather than a single number.

Is Combimist L Inhaler a reliever or a preventer?

It is a reliever. It widens airways that have tightened, but it does nothing about the inflammation behind asthma and COPD — that is what a steroid inhaler such as beclometasone or budesonide is for. Many people keep both: the steroid every day, this inhaler for the tight spells.

How is Combimist L different from a plain salbutamol inhaler?

A salbutamol inhaler carries one bronchodilator. Combimist L carries two: levosalbutamol plus ipratropium bromide, which blocks the nerve signals that keep airway muscle tight. Having a second route to wider airways is the whole difference, and it is why the combination is used in COPD as well as in asthma.

How long does a puff of Combimist L Inhaler last?

The two medicines wear off at different speeds. Levosalbutamol's effect passes within a few hours, while ipratropium's hangs on longer, so a single puff covers a stretch of time rather than a moment. That is also why the inhaler suits a set schedule and not only sudden tightness.

Why does my throat feel dry after using Combimist L Inhaler?

Ipratropium damps nerve signals, and one result is less moisture in the mouth and throat — a familiar effect of anticholinergic medicines. A rinse of water or a few sips after each puff usually eases it.

About Combimist L Inhaler

Two medicines in one canister

Combimist L Inhaler is a pressurised metered-dose inhaler holding two airway-opening drugs. Levosalbutamol, a beta-2 agonist, loosens the muscle circling the small breathing tubes; ipratropium bromide, an anticholinergic, interrupts the nerve messages that keep that muscle clenched. Both asthma and COPD (chronic obstructive pulmonary disease) narrow those tubes, and this inhaler is used for regular control of either condition and for the tight, wheezy spells that come with them. Each press releases 50mcg of levosalbutamol plus 20mcg of ipratropium bromide — the 50/20mcg figure on the pack.

How to use the inhaler

Adults usually take one or two puffs, three or four times a day. Shake the canister and breathe out, then seal your lips around the mouthpiece and press once as you start a slow, deep breath in. Hold that breath for a few seconds and wait about half a minute before a second puff. The levosalbutamol is the quick half, easing a tight chest within minutes; the ipratropium builds more slowly and stays longer, which is why the inhaler fits a regular schedule as well as a bad spell. Afterwards the throat can feel dry, and a mouthful of water sorts it out.

Side effects worth knowing

Trembling hands top the list, along with a quicker or pounding pulse, headache, muscle cramp, a parched mouth or throat, cough and light-headedness. Most are mild and fade over the first days of use, though more frequent puffing makes them stronger; repeated use can leave the voice hoarse.

Breathing that tightens instead of easing straight after a puff, chest pain, a racing or uneven heartbeat, or a rash with swelling of the face, lips or throat needs urgent treatment. Ipratropium can sting the eye, so close your eyes for a second as you press.

Mixing it with other medicines

Beta-blockers, taken for blood pressure, angina or an uneven heart rhythm, work against both ingredients and can leave the chest tighter rather than easier. Other anticholinergic medicines, some bladder and stomach drugs among them, add to the dryness and can affect the eyes and the flow of urine. Some antidepressants and heart-rhythm drugs add to the pulse effect.

Storing and handling

Sun and freezing temperatures are both bad for the canister, so it stays out of the freezer compartment and off the windowsill. It is pressurised, which means it is never pierced or burned, even once it feels empty. An inhaler left in the cold works better after a minute warming in your hand.

Sources

  1. Levalbuterol Oral Inhalation: MedlinePlus Drug Information — National Library of Medicine
  2. Atrovent Inhaler CFC-Free - Summary of Product Characteristics (SmPC) - (emc) | 61 — UK Electronic Medicines Compendium (EMC)