Creon
Creon 150mg capsules contain pancrelipase, the digestive enzymes used in pancreatic enzyme deficiency and cystic fibrosis; packs of 30, 60, 90, 120 or 180 are available.
All strengths and pack prices
| Strength | Pack | Price | Per capsule |
|---|---|---|---|
| 150mg | 30 capsules | $129.90 | $4.33 |
| 150mg | 60 capsules | $250.20 | $4.17 |
| 150mg | 90 capsules | $367.20 | $4.08 |
| 150mg | 120 capsules | $469.20 | $3.91 |
| 150mg | 180 capsules | $675.00 | $3.75 |
- Category
- Digestive Health
- Active ingredient
- Pancrelipase
- Route
- Oral
- Form
- Capsule
- Strengths
- 150mg
You will receive a quality generic equivalent, depending on stock.
Shipped in a discreet, unmarked envelope.
Details
- Conditions
- Pancreatic enzyme deficiency · Cystic fibrosis
- Therapeutic Class
- Digestive Enzyme
- Pharmacological Class
- Pancreatic Enzyme
- Minor Side Effects
- Mild diarrhoea, stomach upset
- Moderate Side Effects
- Constipation, nausea
- Dosage Forms
- Capsule
- Administration Route
- Oral
- Originator
- AbbVie
- Onset Time
- Rapid after ingestion
- Duration
- Duration of meal digestion
- Storage Instructions
- Store at room temperature, keep container tightly closed.
- Drug Interactions
- Calcium supplements, Magnesium supplements
What you will receive
Creon is the originator brand name, made by AbbVie. We use it to identify the medicine; the pack you receive is a generic equivalent, not the original Creon.
- The same active ingredient (Pancrelipase) at the same strength.
- The exact brand supplied depends on what is in stock when your order ships.
FAQ
Which Creon strengths and pack sizes can I order?
Creon comes as capsules in 150mg. You can order packs of 30, 60, 90, 120 or 180 capsules. Larger packs cost less per capsule. It is generic pancrelipase, not the original Creon.
What happens if my generic pancrelipase parcel is damaged in Hong Kong?
If your generic pancrelipase parcel arrives damaged, it is sent again free. If that is not possible, the order is refunded. Orders can be cancelled within 24 hours if not yet dispatched, and support answers 24/7 in English and Cantonese by live chat.
What other names is pancrelipase sold under?
Creon is a brand name of pancrelipase, which is also sold as Pancreaze and Zenpep. Here, pancrelipase can be bought online as generic Creon. These are generics, not the original brand.
Should I take Creon with every meal and snack?
Yes. One goes with each meal and each snack, and with milky drinks or anything else containing fat or protein. The enzymes work only on food that is in the gut at the same time, so a meal taken without a capsule passes through partly undigested.
What should I do if I miss a Creon dose?
Take it with your next meal or snack rather than on its own, then carry on as normal. Do not take two capsules at once to make up for the missed one, and stay within the daily limit.
Can I open a Creon capsule and mix it with food?
When swallowing a capsule is difficult, open the capsule and mix the granules with a spoonful of soft acidic food such as apple puree. Swallow it at once without chewing, then drink water. Do not stir it into milk, formula or breast milk, and throw away anything left over.
How long does Creon take to work?
Each dose acts on the meal it goes with. The granules release their enzymes in the small intestine as food arrives, so there is nothing to build up over days. Greasy stools and bloating tend to ease once the number of capsules suits the fat in your meals.
Does Creon treat pancreatitis itself?
No. They supply enzymes the pancreas is no longer making, so food is broken down and nutrients are absorbed; they do not calm inflammation or ease pancreatic pain. Someone with chronic pancreatitis may take them for years alongside other treatment for the condition.
About Creon
What Creon capsules do
Creon 150mg capsules hold pancrelipase, the enzyme mixture a healthy pancreas releases into the small intestine. It carries three: lipase, which breaks fat down, protease for protein and amylase for starch. Damage from chronic pancreatitis, surgery that removes the pancreas or cystic fibrosis can leave the pancreas unable to supply enough of them. Food then moves through only partly digested, and the shortfall shows up as greasy, bulky stools that are hard to flush, wind, bloating and weight loss. The medical name for that shortfall is exocrine pancreatic insufficiency. The enzymes here are extracted from pig pancreas; taken with a meal, they do the work the pancreas is not doing, so that meal's nutrients can be absorbed.
Taking a capsule with food
Swallow one capsule with each meal and each snack, with a glass of water — several doses a day is normal, because the enzymes have to reach the gut alongside the food they are working on. Chewing a capsule, crushing it or holding it in the mouth lets the enzymes out too early and can irritate the mouth and throat; the coating is what carries them past stomach acid and releases them further down. How much you need follows the fat in your meals, so the number of capsules can change over time, and there is a daily total that should not be exceeded even on days with extra food.
Side effects
Most of what people report is in the gut: bloating, wind, cramps, loose stools, nausea or constipation. These often settle once the number of capsules fits the amount of fat in a meal. Wheezing, a rash that spreads or swelling of the mouth or throat needs urgent help. Fibrosing colonopathy, a rare narrowing of the bowel, has followed years of very high doses, mostly in people with cystic fibrosis, which is why the daily total has a ceiling and is not simply raised when symptoms linger.
The 150mg capsule and storing it
Someone taking capsules with every meal and snack can get through 30 of the 150mg capsules quickly, which is why packs go up to 60, 90, 120 and 180. Enzymes lose potency when they get hot or damp, so the lid goes back on after each use and the container stays away from sun and cooking heat. Granules mixed into food and left uneaten are thrown away, not kept for later. Most people stay on pancrelipase for years, because the pancreas does not start making enzymes again.
Sources
- Pancrelipase: MedlinePlus Drug Information — MedlinePlus / U.S. National Library of Medicine
- Exocrine Pancreatic Insufficiency (EPI) - NIDDK — NIDDK / NIH