Ofev
Ofev is generic nintedanib 100mg capsules, an antifibrotic taken twice daily to slow lung scarring in idiopathic pulmonary fibrosis and other progressive fibrosing lung diseases.
All strengths and pack prices
| Strength | Pack | Price | Per capsule |
|---|---|---|---|
| 100mg | 30 capsules | $164.10 | $5.47 |
| 100mg | 60 capsules | $280.20 | $4.67 |
| 100mg | 90 capsules | $387.00 | $4.30 |
| 100mg | 120 capsules | $468.00 | $3.90 |
| 100mg | 180 capsules | $1,171.80 | $6.51 |
- Category
- Respiratory Health · COVID-19 Support
- Active ingredient
- Nintedanib
- Route
- Oral
- Form
- Capsule
- Strengths
- 100mg
You will receive a quality generic equivalent, depending on stock.
Shipped in a discreet, unmarked envelope.
Details
- Conditions
- Idiopathic Pulmonary Fibrosis
- Therapeutic Class
- Tyrosine kinase inhibitor
- Pharmacological Class
- Antifibrotic
- Minor Side Effects
- Diarrhoea, Nausea
- Moderate Side Effects
- Abdominal pain, Decreased appetite
- Dosage Forms
- Capsule
- Administration Route
- Oral
- Originator
- Boehringer Ingelheim
- Storage Instructions
- Keep dry at room temperature.
- Drug Interactions
- Rifampin, St. John's Wort
- Age Restrictions
- Not for children.
What you will receive
Ofev is the originator brand name, made by Boehringer Ingelheim. We use it to identify the medicine; the pack you receive is a generic equivalent, not the original Ofev.
- The same active ingredient (Nintedanib) at the same strength.
- The exact brand supplied depends on what is in stock when your order ships.
FAQ
Which Ofev 100mg pack sizes can I order?
Ofev comes as 100mg capsules in packs of 30 to 180. This is generic nintedanib, not the original Ofev.
How is Ofev delivered to Hong Kong?
For a long course of Ofev, tracked courier takes 5 to 9 business days with online tracking. Standard airmail takes 14 to 21 business days, 30 at most, and is untracked. Very large orders over 120 units may be split into several parcels.
Can I take Ofev with food?
Yes — each capsule should be taken with a meal. Food is part of how the medicine is taken rather than an optional extra, and having it with breakfast and dinner makes it easier to keep the two doses about twelve hours apart.
What happens if I forget a dose of Ofev?
If you miss a capsule, leave it out and take your next dose when it is due. Taking two together to make up for it is not how nintedanib is taken.
Is Ofev the same as nintedanib?
Yes. Ofev is a brand name for nintedanib, and the capsules sold here contain that same active ingredient. They are taken the same way: one 100mg capsule twice a day with meals.
Can I smoke while taking Ofev?
Cigarette smoking can make nintedanib work less well, so it is worth stopping before the first dose and staying off cigarettes for as long as you take the capsules.
How long does Ofev take to work?
Its effect builds over months rather than days — there is nothing to notice after a single capsule. Nintedanib works on a slow scarring process, and the change it makes shows up in lung function tests over a long course of treatment.
About Ofev
What these capsules are used for
Ofev capsules contain nintedanib, a medicine for people whose lungs are becoming scarred and stiff. It is used when no cause can be found for that scarring — idiopathic pulmonary fibrosis — and for several other long-term scarring lung conditions that worsen with time. It is also used when systemic sclerosis, a hardening of the skin and internal organs, has affected the lungs. The aim is to slow the loss of lung function; it does not remove scar tissue that has already formed. What is sold here is generic nintedanib 100mg capsules under the Ofev name.
How it works
Nintedanib is a kinase inhibitor. It blocks enzymes and growth-factor receptors that signal lung tissue to build fibrous scar material, so with those signals dampened, less new scar tissue forms. It is not an infection treatment, and it will not help during a sudden bout of breathlessness.
Taking the capsules
The dose is one capsule in the morning and one in the evening, about twelve hours apart, each with a meal. Swallow the capsules whole; they are not chewed, crushed or opened. A forgotten dose is simply left out, and the next capsule is taken at its usual time. Keep the capsules in their original pack, somewhere cool and dry.
Side effects
Loose stools are the most frequent complaint, and nausea, vomiting, stomach cramps, appetite loss and weight loss can appear in the early weeks. Diarrhoea sometimes becomes bad enough that the dose has to be reduced. The serious risk is liver injury, which shows up as pain under the ribs on the right, yellowing skin or eyes, dark urine or deep tiredness. Unusual bleeding or bruising needs urgent attention.
Other medicines and smoking
St John's wort cuts the amount of nintedanib in the blood, so the two should not be taken together. Smoking has much the same effect, and it is worth giving up cigarettes before the first capsule. Other drugs that act on the liver enzymes which break nintedanib down can raise or lower its level in the body. Because it can damage a developing baby, nintedanib is not used during pregnancy.
Sources
- Nintedanib: MedlinePlus Drug Information — National Library of Medicine
- Idiopathic Pulmonary Fibrosis (IPF) - American Lung Association — American Lung Association