Phenergan Syrup
Phenergan Syrup

7.82
Phenergan Syrup is a multi-action antihistamine used for the management of allergic symptoms, nausea, vomiting, and as a mild sedative.


Ingredient
Availability
In Stock
Delivery
Airmail (14-21 days) | EMS trackable (5-9 days)
Product is shipped in a fully discreet envelope with no content disclosure, including all required documentation inside

Product Sheet

Active Ingredient(s)
Promethazine
Reference Brand
Promethazine
Product Origin
Generic Alternative
Reference Manufacturer
Sanofi
Product Form
Syrup
Regulatory Classification
Rx
Primary Category
Allergy Relief
Product Category
Antihistamine
Pharmacological Class
Phenothiazine
Clinical Indications
Allergic conditions, Nausea, Sedation
Manufacturer Description
Phenergan Syrup is a multi-action antihistamine used for the management of allergic symptoms, nausea, vomiting, and as a mild sedative.
Mechanism of Action
Promethazine competitively antagonizes central and peripheral H1-receptors and exhibits anticholinergic properties, providing anti-allergic, antiemetic, and sedative effects.
Route of Administration
Oral
Contraindications
Severe respiratory conditions, Children under 2
Severe Adverse Events
Respiratory depression
Common Side Effects
Drowsiness, Dry mouth
Uncommon Side Effects
Blurred vision, Dizziness
Drug Interactions
Alcohol, Sedatives
Pregnancy Safety Warnings
Discuss with a doctor.
Age Restrictions
Use with caution in children; contraindicated under 2.
Storage Guidelines
Store away from heat and light.
Related Products
Diphenhydramine

Phenergan Syrup FAQ

Can I travel internationally with Phenergan Syrup?

Yes, Phenergan Syrup can be taken on international flights, but you should keep the medication in its original packaging with a copy of the prescription. Some countries require a declaration for prescription medicines, so check the destination’s import rules in advance.

Does Phenergan Syrup contain any sugars or allergens?

The syrup formulation typically includes sweeteners and flavoring agents, which may contain sugars or trace allergens such as corn syrup. Review the product’s ingredient list or ask your pharmacist if you have specific dietary restrictions.

Will taking Phenergan Syrup affect my ability to drive?

Promethazine can cause drowsiness and slowed reaction times. It is advisable to avoid operating vehicles or heavy machinery until you know how the medication affects you personally.

Is Phenergan Syrup safe for use during pregnancy?

Promethazine is classified as a Category C drug in many jurisdictions, meaning risk cannot be ruled out. It should be used during pregnancy only if the potential benefit outweighs the potential risk, and always under medical supervision.

How does the taste of Phenergan Syrup compare to other antihistamine syrups?

The syrup is flavored to mask the bitter taste of promethazine, often described as mildly sweet with a slight medicinal aftertaste. Individual perception may vary, and using a small amount of food or drink can help improve palatability.

Can I take Phenergan Syrup with other antihistamines?

Combining Phenergan Syrup with other antihistamines can increase sedation and anticholinergic side effects. This combination should only be undertaken after a clinician evaluates the need and monitors for adverse effects.

What should I do if I accidentally swallow a larger dose than prescribed?

If you suspect an overdose, seek emergency medical attention immediately. Symptoms may include extreme drowsiness, difficulty breathing, or irregular heartbeats. Prompt treatment is essential.

Is there a generic version of Phenergan Syrup available in Hong Kong?

Promethazine syrup is available in both brand-name (Phenergan) and generic forms. The active ingredient is identical, but inactive ingredients and bottle appearance may differ. Check with your pharmacist for local generic options.

How long can an opened bottle of Phenergan Syrup be used?

After opening, the syrup should be used within 30 days if stored at room temperature and the cap is tightly sealed. Discard any remaining product after this period or if you notice changes in appearance or smell.

Does Phenergan Syrup interact with alcohol?

Yes, alcohol can intensify the sedative effects of promethazine, leading to increased drowsiness or dizziness. It is best to avoid alcohol while taking the syrup.

What is Promethazine?

Regulating histamine levels in the body, promethazine operates as a primary active ingredient in formulations commonly referred to as Phenergan Syrup or similar antihistamine products. This compound belongs to the phenothiazine chemical class, functioning primarily to address symptoms related to seasonal allergies, hives, and motion sickness. By interacting with physiological response systems, it provides a method for managing discomfort related to allergic reactions or nausea.

The substance acts as a sedative and antiemetic agent, meaning it is often utilized to assist with sleep in clinical settings or to manage feelings of faintness or sickness. It is designed for oral administration, where it enters the systemic circulation to modulate histamine receptors. Many formulations available in Hong Kong include this ingredient as the primary component for addressing acute symptoms when other, non-sedating options are considered insufficient.

Formulations and Common Applications

Promethazine syrup remains a frequent choice for liquid-based delivery, offering controlled administration for both adults and pediatric populations. In the Hong Kong market, this ingredient appears in various proprietary syrup formats under different labels. While specific branded versions are commonly identified by the public, the pharmacological function remains identical across the generic versions of these solutions. Selecting between regional alternatives often depends on the concentration of the API within the syrup, which varies by manufacturer.

Therapeutic Applications

  • Allergic Rhinitis: Managing seasonal discomfort, including sneezing, itchy eyes, and nasal congestion caused by environmental triggers.
  • Urticaria: Addressing inflammatory skin responses such as hives or itching (pruritus) characterized by elevated red welts.
  • Motion Sickness: Assisting in the reduction of sensations of dizziness or vomiting associated with travel by vehicle, sea, or air.
  • Sleep Support: Utilizing the sedative properties of the compound to address short-term difficulty with falling asleep in specific clinical contexts.

Biological Action

Upon ingestion, the compound enters the circulatory system and crosses the blood-brain barrier to exert its influence. It binds to H1-receptors, effectively blocking the actions of histamine, which is a chemical released by the body during an allergic response. By inhibiting these receptors, the substance prevents the cascade of symptoms such as swelling, itching, and capillary leakage. Furthermore, its secondary effects on different brain pathways contribute to its reputation for calming the body and reducing nausea.

Safety Profile

Common Reactions

Patients may occasionally experience dryness of the mouth, throat, or nose, alongside mild feelings of lethargy or drowsiness. These effects are often transient and tend to subside as the body acclimatizes to the substance.

Serious Reactions

Immediate medical assessment is required if an individual experiences involuntary muscle movements, severe confusion, or signs of an irregular heartbeat. Difficulty breathing or significant swelling of the face and throat are also indicators that demand professional intervention.

Contraindications

The use of this ingredient requires caution among individuals with a history of breathing disorders like asthma or those with specific underlying cardiovascular conditions. Pregnant or nursing individuals should avoid this substance unless explicitly evaluated by a healthcare professional, as the compound can cross physiological barriers.

Interaction Awareness

Combining this syrup with central nervous system depressants, such as alcohol or specific sedatives, can intensify the substance's effects significantly. Please review the specific medication's insert to identify the complete list of contraindications and potential interactions relevant to your current regimen.

Usage Context and Considerations

Proper storage of syrup formulations involves keeping the container in a cool, dark location away from direct sunlight and humidity to maintain its chemical stability. The duration of use is typically limited to the resolution of acute symptoms, rather than long-term management. Because this substance can affect motor coordination, it is frequently recommended that users avoid operating heavy machinery or driving shortly after administration. For detailed usage, dosing, and administration, refer to the specific medication's clinical information.

Glossary

Antiemetic
A substance used to prevent or reduce nausea and vomiting.
Histamine
A chemical messenger released by immune cells that causes symptoms like itching and swelling during an allergic reaction.
Phenothiazine
A class of chemical compounds known for their significant effects on the central nervous system and their ability to block various receptors in the body.

Important Safety Information

This text serves as an educational overview regarding promethazine and should not be interpreted as professional medical advice. Individual medications like Phenergan Syrup vary significantly in strength, concentration, and specific formulation, which may influence how they affect your physiology. No liability is assumed for the clinical application of this information; patients must always consult the specific medication labeling and a licensed healthcare professional to determine if this therapy is appropriate for their needs.

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