Vfend
Vfend 200mg tablets hold voriconazole, a triazole antifungal used for invasive aspergillosis and other serious fungal infections, in packs of 4, 12 or 20.
All strengths and pack prices
| Strength | Pack | Price | Per tablet |
|---|---|---|---|
| 200mg | 4 tablets | $187.00 | $46.75 |
| 200mg | 12 tablets | $420.72 | $35.06 |
| 200mg | 20 tablets | $624.00 | $31.20 |
- Category
- Antifungals
- Active ingredient
- Voriconazole
- Route
- Oral
- Form
- Tablet, Injection
- Strengths
- 200mg
You will receive a quality generic equivalent, depending on stock.
Shipped in a discreet, unmarked envelope.
Details
- Conditions
- Invasive aspergillosis · Severe fungal infections
- Therapeutic Class
- Triazole Antifungal
- Pharmacological Class
- Antifungal
- Minor Side Effects
- Visual disturbances, Rash, Fever
- Moderate Side Effects
- Nausea, Vomiting, Liver enzyme level changes
- Dosage Forms
- Tablet, Injection
- Administration Route
- Oral
- Originator
- Pfizer
- Onset Time
- Not specified
- Storage Instructions
- Store at room temperature.
- Drug Interactions
- Rifampin, Carbamazepine, Quinidine
- Age Restrictions
- Safety in paediatric patients under 2 requires medical assessment.
What you will receive
Vfend is the originator brand name, made by Pfizer. We use it to identify the medicine; the pack you receive is a generic equivalent, not the original Vfend.
- The same active ingredient (Voriconazole) at the same strength.
- The exact brand supplied depends on what is in stock when your order ships.
FAQ
Which Vfend strengths and pack sizes can I order?
Vfend pages list 200mg tablets in packs of 4, 12 or 20. The pack contains generic voriconazole, not the original Vfend. Larger packs cost less per tablet.
How discreet is Vfend delivery to Hong Kong?
Vfend orders to Hong Kong ship in plain, unbranded packaging with nothing on the outside about the contents. If a parcel does not arrive within its delivery window or arrives damaged, it is sent again free; if that is not possible, the order is refunded.
How long does Vfend treatment usually last?
There is no set number of days. It depends on which fungus is being treated, how quickly it responds and how well you are in yourself. Mould infections are slow to clear, so several weeks is common and some courses run for months. Feeling better is not the point to stop.
Is Vfend available as a liquid or an injection?
Vfend here is sold as tablets only. Voriconazole is also made as an oral suspension, which helps if tablets are hard to swallow, and as an infusion given in hospital. Suspension is measured with the dosing device in the pack, not a kitchen spoon.
What is invasive aspergillosis?
Aspergillus is a mould found in soil, dust and decaying plant matter, and its spores are breathed in constantly without harm by most people. Invasive aspergillosis is when the mould starts growing in the lungs, usually in someone whose defences are low, and then spreads to other organs.
Is Vfend the same as fluconazole?
No. Both are azole antifungals, but fluconazole is the one used for yeasts such as Candida, while voriconazole also reaches moulds like Aspergillus, which is why it is used for aspergillosis and for infections that have not answered other treatment.
Does Vfend affect eyesight?
Voriconazole often affects sight, and it is the side effect people notice most. Colours can seem different, bright light may feel harsh, and vision may blur for short spells. It tends to appear in the first days of treatment and to bother people less as time passes.
About Vfend
What the tablets treat
Voriconazole is for fungal infections that have got inside the body. The best known is invasive aspergillosis. Spores of a common mould are breathed in, settle in the lungs and travel in the blood to other organs. The tablets also treat candidaemia, a yeast infection in the bloodstream, and oesophageal candidiasis, which leaves white patches in the food pipe and makes swallowing painful. Rarer mould infections are treated with it when other antifungals have failed. Most patients have a weakened immune system or damaged lungs.
How voriconazole works
A fungal cell membrane is held together by ergosterol. Voriconazole blocks one step in making it, so the fungus cannot divide or spread and the immune system clears it. Human cells are built differently and are not affected in the same way.
Taking your dose
The usual routine is one 200mg tablet in the morning and one in the evening, evenly spaced so the level in the blood stays steady. Take it with water and keep an hour clear of food on either side, since a meal close to the tablet cuts how much is absorbed. Mould and yeast infections clear slowly, so expect weeks of treatment, continuing after you start to feel better.
Side effects worth knowing
Vision is often the first thing people notice after starting voriconazole. Colours may look odd, bright light may be uncomfortable, and vision can go briefly soft; these changes are usually mild and fade as the course continues. Headache, nausea, vomiting, diarrhoea, stomach pain, fever and skin rash are the other common ones. Liver injury is uncommon but serious — yellowing of the skin and the whites of the eyes, dark urine, or pain below the ribs on the right side needs urgent treatment. Heart rhythm can also be disturbed, and the skin burns more easily in sunshine, so cover up outdoors.
Other medicines to be careful with
The enzyme that clears voriconazole is used by plenty of other drugs too, so levels can drift when they are combined. Blood thinners such as warfarin, immunosuppressants given after a transplant, benzodiazepine sedatives and omeprazole come up most often. St John's wort, an over-the-counter herbal remedy, works the other way and can leave too little voriconazole in the body; it should not be taken during a course.
Sources
- Voriconazole: MedlinePlus Drug Information — National Library of Medicine
- Aspergillosis | Fungal Diseases | CDC — CDC