Diclegis
Doxylamine Succinate · Pyridoxine
Diclegis is a delayed-release tablet of doxylamine succinate 10mg with pyridoxine 10mg (vitamin B6), used for nausea and vomiting in pregnancy, available in packs of 30 to 180 tablets.
All strengths and pack prices
| Strength | Pack | Price | Per tablet |
|---|---|---|---|
| 10/10mg | 30 tablets | $62.10 | $2.07 |
| 10/10mg | 60 tablets | $108.60 | $1.81 |
| 10/10mg | 90 tablets | $155.70 | $1.73 |
| 10/10mg | 120 tablets | $194.40 | $1.62 |
| 10/10mg | 180 tablets | $280.80 | $1.56 |
- Category
- Women's Health
- Active ingredient
- Doxylamine Succinate · Pyridoxine
- Route
- Oral
- Form
- Delayed-release tablet
- Strengths
- 10/10mg
You will receive a quality generic equivalent, depending on stock.
Shipped in a discreet, unmarked envelope.
Details
- Therapeutic Class
- Antihistamine, Vitamin B6
- Pharmacological Class
- Antiemetic
- Minor Side Effects
- Drowsiness
- Moderate Side Effects
- Dry mouth
- Dosage Forms
- Delayed-release tablet
- Administration Route
- Oral
- Originator
- Duchesnay
- Onset Time
- 1–2 hours
- Duration
- 8 hours
- Storage Instructions
- Store at room temperature.
- Drug Interactions
- Alcohol, Sedatives
What you will receive
Diclegis is the originator brand name, made by Duchesnay. We use it to identify the medicine; the pack you receive is a generic equivalent, not the original Diclegis.
- The same active ingredient (Doxylamine Succinate / Pyridoxine) at the same strength.
- The exact brand supplied depends on what is in stock when your order ships.
FAQ
Which Diclegis pack sizes can I order?
The pack contains generic doxylamine succinate + pyridoxine tablets, not the original Diclegis. It comes in 10/10mg strength, in packs of 30, 60, 90, 120 or 180 tablets. Larger packs cost less per tablet.
Can my Diclegis order be split for delivery to Hong Kong?
For Diclegis, very large orders over 120 units may be split into several parcels. Every order ships in plain, unbranded packaging with nothing outside about the contents. Tracked courier takes 5 to 9 business days with online tracking; standard airmail takes 14 to 21 business days, 30 at most.
What other names is doxylamine succinate and pyridoxine sold under?
Diclegis is a brand name of doxylamine succinate and pyridoxine, which are also sold as Doxinate. Here, doxylamine succinate and pyridoxine can be bought online as generic Diclegis. These are generics, not the original brand.
What is the difference between Diclegis and vitamin B6 on its own?
Vitamin B6 (pyridoxine) is used on its own for mild sickness in pregnancy. This tablet adds doxylamine, an antihistamine that calms the vomiting signal in the brain, and the pair is the combination used for mild to moderate nausea and vomiting. It is also mildly sedating, which plain vitamin B6 is not.
Does Diclegis make you drowsy?
Yes — doxylamine is an antihistamine, and sleepiness is the effect people notice most. That is why the tablets are usually taken at bedtime. Dry mouth and a spell of dizziness when you stand up can come with it. The drowsiness can affect driving and any work that needs steady concentration.
Can I drink alcohol while taking Diclegis?
Alcohol makes the drowsiness and light-headedness worse, and it stacks with other sedating medicines: sleep aids, cough and cold remedies that contain antihistamines, and opioid painkillers. It adds to the dry mouth as well.
What does delayed-release mean on this tablet?
It means the tablet releases doxylamine and pyridoxine gradually as it passes through the gut, instead of all at once, so the effect is spread over a longer stretch. Delayed-release tablets should be swallowed whole with water; crushing, chewing or splitting one releases the contents too quickly.
How long will I need to take Diclegis?
That depends on your symptoms rather than a fixed number of weeks. Sickness in pregnancy usually starts between weeks 4 and 10 and eases by around week 20 for most women, so many people need the tablets for a stretch in early pregnancy and less as it passes.
About Diclegis
A doxylamine and vitamin B6 tablet for nausea in pregnancy
Diclegis here is a delayed-release tablet of doxylamine succinate 10mg with pyridoxine 10mg — pyridoxine is vitamin B6. It is taken for nausea and vomiting in pregnancy, the sickness usually called morning sickness even though it often runs through the whole day. Around seven in ten pregnancies are affected, most commonly from about week 4 to week 10. One strength is stocked, 10/10mg, in packs of 30 up to 180 tablets.
How the two ingredients work together
Doxylamine is an antihistamine. It quietens the signals in the brain that trigger the urge to vomit, and it is mildly sedating, which is part of how it helps you rest through a rough patch. Vitamin B6 on its own is used for milder sickness; the two together are the combination used for mild to moderate nausea and vomiting in pregnancy, including when small, bland, dry meals and frequent snacking have not settled things.
Swallowed whole, usually at bedtime
Doxylamine makes most people sleepy, so the tablet normally goes down at bedtime, and some people add one at the time of day when the sickness is worst. It is a delayed-release tablet: swallow it whole with water, because chewing, crushing or splitting it lets the whole dose out at once. Keep to the same times each day for as long as the nausea lasts.
Side effects and what stacks with them
Expect drowsiness, dry mouth and a moment of light-headedness when you stand up quickly. Blurred vision and constipation are possible too, all of them down to the antihistamine, and they tend to be strongest in the first few days or after any increase in how much you take. Alcohol adds to the sleepiness, as do sleep aids, cough and cold remedies with antihistamines, and opioid painkillers. Antidepressants called MAO inhibitors can sharpen the dry mouth and constipation. A rash with swelling of the face, lips or tongue, or trouble breathing, is not an expected reaction to these tablets.
Keeping the tablets
Keep them in their blister in a cool, dry spot, out of direct sunlight and away from damp. Nothing about the tablets changes with the pack size, so the choice is simply how many you want on hand.
Sources
- Nausea and Vomiting During Pregnancy | AFP — American Academy of Family Physicians