Metformin + Glyburide
Metformin + Glyburide combines two oral diabetes medicines in one tablet for type 2 diabetes, sold in 2.5/400mg and 5/500mg strengths.
All strengths and pack prices
| Strength | Pack | Price | Per tablet |
|---|---|---|---|
| 2.5/400mg | 30 tablets | $34.80 | $1.16 |
| 2.5/400mg | 60 tablets | $39.00 | $0.65 |
| 2.5/400mg | 90 tablets | $48.60 | $0.54 |
| 2.5/400mg | 120 tablets | $56.40 | $0.47 |
| 2.5/400mg | 180 tablets | $70.20 | $0.39 |
| 5/500mg | 30 tablets | $37.50 | $1.25 |
| 5/500mg | 60 tablets | $42.00 | $0.70 |
| 5/500mg | 90 tablets | $55.80 | $0.62 |
| 5/500mg | 120 tablets | $64.80 | $0.54 |
| 5/500mg | 180 tablets | $84.60 | $0.47 |
- Category
- Diabetes Management
- Route
- Oral
- Form
- Tablet
- Strengths
- 2.5/400/5/500mg
You will receive a quality generic, depending on stock.
Shipped in a discreet, unmarked envelope.
Details
- Conditions
- Type 2 diabetes
- Therapeutic Class
- Biguanide, Sulfonylurea
- Pharmacological Class
- Antihyperglycemic
- Minor Side Effects
- Nausea, Diarrhoea, Stomach upset
- Moderate Side Effects
- Hypoglycaemia, Weight changes, Metallic taste
- Dosage Forms
- Tablet
- Administration Route
- Oral
- Originator
- Sanofi
- Onset Time
- 1–3 hours
- Duration
- 12–24 hours
- Storage Instructions
- Store in a cool, dry place away from light.
- Drug Interactions
- Cimetidine, Alcohol, Steroids
What you will receive
Metformin + Glyburide is a generic medicine sold under the name of its active ingredient, Glyburide / Metformin.
- The manufacturer depends on what is in stock when your order ships.
- It contains the same active ingredient, at the same strength, as the brand-name versions.
FAQ
Which Metformin + Glyburide strengths and pack sizes can I order?
Two strengths, 2.5/400mg and 5/500mg, each in packs from 30 up to 180 tablets. A tablet costs less in the bigger packs.
What payment methods can I use for Metformin + Glyburide to Hong Kong?
Visa, Mastercard or American Express on an encrypted payment page, so your card number never touches our servers, or Bitcoin or Ethereum. The parcel itself is plain, with no branding.
What are the brand names for metformin and glyburide?
A brand name for metformin and glyburide is Glucovance. Metformin and glyburide tablets are a pure generic metformin and glyburide product and are not that brand. Here, metformin and glyburide can also be bought online as generic Glucovance.
How long does Metformin + Glyburide take to work?
Glyburide is the quick one: its effect on blood sugar begins within hours, so day one already counts. Metformin takes a week or two to give its full share. After that the tablets simply keep readings down for as long as they are taken.
Can I drink alcohol with Metformin + Glyburide?
Alcohol and these tablets do not mix well. It raises the risk of lactic acidosis while metformin is being taken and can tip blood sugar too low with glyburide, particularly on an empty stomach. A meal alongside a drink makes the low less likely.
Is Metformin + Glyburide the same as taking metformin and glyburide as two separate tablets?
The two medicines are the same either way; only the packaging differs. A combined tablet suits people whose doses of each are already settled, while separate tablets allow one medicine to be adjusted or stopped without changing the other.
Can I take Metformin + Glyburide with other diabetes medicines?
Yes, it is often used with insulin or another diabetes tablet. Two sugar-lowering medicines together make a low more likely than one, so blood sugar readings are worth checking more closely whenever a new diabetes medicine is started or a dose changes.
Should I take Metformin + Glyburide with food?
With a meal — breakfast is the usual choice. Food eases the nausea and loose stools metformin can cause, and it matters for glyburide too: a dose taken when a meal is skipped or delayed is more likely to push blood sugar too low.
About Metformin + Glyburide
Two diabetes medicines in one tablet
In type 2 diabetes the body's own insulin stops working properly, and sugar builds up in the blood. Metformin + Glyburide tablets bring together two medicines that lower it in different ways. Metformin belongs to the biguanides: it reduces the sugar the liver puts out, limits how much is absorbed from a meal, and makes muscle and fat tissue more responsive to insulin. Glyburide is a sulphonylurea, which tells the pancreas to release more insulin. Glyburide only helps a pancreas that still makes insulin, which is why the pair is for type 2 diabetes rather than type 1.
It is usually offered when diet, exercise and one diabetes medicine have not brought sugar low enough. It works only while you keep taking it, and it does not cure diabetes.
How to take the tablets
Take one with a meal, most often breakfast or the first main meal; some people take a second dose with their evening meal. Keeping to the same times daily holds the effect steady. Swallow with water. The two strengths, 2.5/400mg and 5/500mg, set how much of each medicine a tablet holds, so the balance depends on the strength chosen.
Keep the pack somewhere cool and out of the sun; heat and damp spoil tablets over time.
Side effects to expect
Metformin is the one that upsets the stomach: nausea, loose stools, diarrhoea and a metallic taste are common at first and often ease off. Glyburide can take blood sugar too low, particularly if a meal is delayed or skipped, and it may add a little weight. Trembling, sweating, hunger, a fast pulse and muddled thinking are how a low shows itself. Lactic acidosis is rare but serious — acid collecting in the blood — with warning signs such as unusual tiredness, aching muscles, stomach pain, heavy or quick breathing and feeling cold; that needs urgent treatment. Rarely, glyburide affects the liver or blood; yellowing of the skin or eyes is the sign.
Alcohol and other medicines
Alcohol pulls this tablet in two directions at once. The metformin half makes lactic acidosis more likely when you drink, and the glyburide half can drive blood sugar too low, which is worst when there is no food in the stomach. Other glucose-lowering medicines, including insulin, add to the low-sugar risk. Topiramate, zonisamide and acetazolamide raise the lactic acidosis risk. Ibuprofen and similar painkillers can make glyburide hit harder.
Metformin + Glyburide or Glucovance?
Both hold the same medicines in the same tablet form; what differs is the brand name. Glucovance is the branded version, while this one carries the ingredient names on the pack in the same two strengths.
Sources
- Metformin: MedlinePlus Drug Information — MedlinePlus / National Library of Medicine
- Glyburide: MedlinePlus Drug Information — MedlinePlus