Midodrine
Midodrine 2.5mg tablets are taken when blood pressure drops too far on standing, a problem called orthostatic hypotension. Packs of 20, 60 and 120 tablets.
All strengths and pack prices
| Strength | Pack | Price | Per tablet |
|---|---|---|---|
| 2.5mg | 20 tablets | $78.20 | $3.91 |
| 2.5mg | 60 tablets | $210.60 | $3.51 |
| 2.5mg | 120 tablets | $390.00 | $3.25 |
- Category
- Heart & Blood Pressure
- Active ingredient
- Midodrine
- Route
- Oral
- Form
- Tablet
- Strengths
- 2.5mg
You will receive a quality generic, depending on stock.
Shipped in a discreet, unmarked envelope.
Details
- Conditions
- Orthostatic hypotension
- Therapeutic Class
- Alpha-agonist
- Pharmacological Class
- Vasopressor
- Minor Side Effects
- Scalp tingling, Goosebumps, Itching
- Moderate Side Effects
- Peeing difficulty, Elevated blood pressure
- Dosage Forms
- Tablet
- Administration Route
- Oral
- Originator
- Shire
- Onset Time
- 20–40 minutes
- Duration
- 3–4 hours
- Storage Instructions
- Store at room temperature.
- Drug Interactions
- Stimulants, Decongestants
What you will receive
Midodrine is a generic medicine sold under the name of its active ingredient, Midodrine.
- The manufacturer depends on what is in stock when your order ships.
- It contains the same active ingredient, at the same strength, as the brand-name versions.
FAQ
Which Midodrine pack sizes can I order?
You can order Midodrine as 2.5mg tablets in packs of 20, 60 or 120 tablets. Larger packs cost less per tablet.
How is Midodrine delivered to Hong Kong?
Midodrine delivery to Hong Kong uses tracked courier in 5 to 9 business days with online tracking. Order tracking is on the tracking page, and support answers 24/7 in English and Cantonese by live chat. Every parcel ships in plain, unbranded packaging with nothing on the outside about the contents.
Which brand names does midodrine have?
Brand names for midodrine include Gutron, Proamatine, Orvaten and Bramox. Midodrine tablets are a pure generic midodrine product and are not any of those brands. Here, midodrine can also be bought online as generic Gutron.
How long does one midodrine dose last?
Each tablet works for a few hours rather than a full day. That short action is why midodrine is taken two or three times across the waking hours instead of once each morning, and why the timing of the last dose of the day matters so much.
Can I drink alcohol with midodrine?
Alcohol widens blood vessels and lowers blood pressure, working against what midodrine is doing. A heavy night can leave you more lightheaded on standing the next morning, and it can also bring on a headache or a racing pulse.
Is midodrine the same as fludrocortisone?
No, they raise blood pressure in different ways. Midodrine tightens blood vessels within minutes of a dose. Fludrocortisone is a steroid that makes the kidneys hold on to sodium and water, so blood volume builds up over days. The two are sometimes combined.
Why does midodrine make my scalp tingle?
The tingling comes from the same receptor midodrine targets in blood vessels. Alpha-1 receptors also sit on the small muscles that make each hair stand up, so when the drug reaches them the scalp prickles and goosebumps appear. It means the dose is active.
Can midodrine make it harder to pass urine?
It can. The bladder neck and the muscle that holds urine in are controlled by the same alpha-1 receptors, and tightening them makes starting a flow harder or creates a sudden sense of urgency. This is a known effect of the medicine rather than a bladder infection.
About Midodrine
What midodrine does to blood pressure
Standing up should not make the room tilt. When it does — a wash of dizziness, dimmed vision, sometimes a faint — the cause is often blood pressure that falls as the body rises. Midodrine is taken to blunt that fall, a condition called orthostatic hypotension, and it is used when the dizziness is still getting in the way of ordinary days. The body turns midodrine into desglymidodrine, which stimulates alpha-1 receptors on the walls of blood vessels. The vessels narrow, so the pressure inside them climbs. Its work is on the vessels rather than the heart's pumping, and each dose is short-lived.
The tablets here are 2.5mg of midodrine hydrochloride each, sold in packs of 20, 60 or 120.
How to take it during the day
Because each dose is short-lived, midodrine is spread over the hours you are awake rather than taken once. One tablet three times a day is the usual pattern, three to four hours apart, with the final tablet at least four hours before bedtime so pressure is not raised while you lie flat. Swallow it with water; meals do not matter.
Why your scalp may tingle
A prickling or itching scalp is the giveaway that a dose is working, sometimes with goosebumps or a shiver. It is not an allergic reaction: alpha-1 receptors sit on the tiny muscles at the base of each hair, and the drug is squeezing them. Headache, a queasy stomach, heartburn and a sudden urge to pass urine are also common, and most of these settle as the routine becomes familiar.
When pressure climbs too far
The effect that matters most is blood pressure rising while you lie down. A pounding headache, blurred vision, ringing in the ears or a pulse that feels unusually slow are the signs. Cold and flu remedies with a decongestant, stimulants and other medicines that narrow blood vessels push the same way, and MAO inhibitors are avoided with midodrine. Digoxin and beta-blockers slow the heart further, and blood pressure tablets work against midodrine.
Sources
- Orthostatic Hypotension | National Institute of Neurological Disorders and Stroke — National Institute of Neurological Disorders and Stroke
- Low blood pressure (hypotension) - NHS — National Health Service