Methotrexate
Methotrexate 2.5mg tablets are used for rheumatoid arthritis, psoriasis and some cancers; this antimetabolite listing comes in packs of 30, 60, 90 or 120 tablets.
All strengths and pack prices
| Strength | Pack | Price | Per tablet |
|---|---|---|---|
| 2.5mg | 30 tablets | $25.80 | $0.86 |
| 2.5mg | 60 tablets | $46.20 | $0.77 |
| 2.5mg | 90 tablets | $67.50 | $0.75 |
| 2.5mg | 120 tablets | $87.60 | $0.73 |
- Category
- Autoimmune Support · Oncology Support
- Active ingredient
- Methotrexate
- Route
- Oral
- Form
- Tablet, Injection
- Strengths
- 2.5mg
You will receive a quality generic, depending on stock.
Shipped in a discreet, unmarked envelope.
Details
- Conditions
- Rheumatoid arthritis · Psoriasis · Cancer
- Therapeutic Class
- Antimetabolite
- Pharmacological Class
- Folate antagonist
- Minor Side Effects
- Nausea, Fatigue
- Moderate Side Effects
- Mouth sores, Hair loss
- Dosage Forms
- Tablet, Injection
- Administration Route
- Oral
- Originator
- Pfizer
- Onset Time
- Few weeks
- Duration
- Weekly
- Storage Instructions
- Store away from heat and light.
- Drug Interactions
- NSAIDs, Penicillins, Probenecid
- Age Restrictions
- Consult specialist
What you will receive
Methotrexate is a generic medicine sold under the name of its active ingredient, Methotrexate.
- The manufacturer depends on what is in stock when your order ships.
- It contains the same active ingredient, at the same strength, as the brand-name versions.
FAQ
Which Methotrexate pack sizes can I order?
You can order Methotrexate as 2.5mg tablets in packs of 30, 60, 90 or 120 tablets. Larger packs cost less per tablet.
How is Methotrexate delivered to Hong Kong?
Methotrexate for Hong Kong can arrive by standard airmail in 14 to 21 business days, up to 30 at most, and is untracked. Every order ships in plain, unbranded packaging with nothing on the outside about the contents. If it does not arrive within the delivery window or arrives damaged, it is sent again free or refunded if that is not possible.
What are the other names for methotrexate?
Brand names for methotrexate include Rheumatrex, Metoject and Trexall. Methotrexate tablets are a pure generic methotrexate product and are not any of those brands.
Why is methotrexate taken once a week rather than every day?
A weekly dose is enough to calm inflammation, but the medicine leaves the body slowly and builds up if it is taken daily. Daily dosing pushes blood levels much higher and sharply increases the risk of bone marrow, liver and mouth problems. The seven-day gap is what makes long-term treatment workable.
How long does methotrexate take to work for rheumatoid arthritis?
Think in months. Someone who wakes with stiff, swollen hands may see a little easing after a few weeks, but the full effect usually takes three months or longer. Psoriasis and psoriatic arthritis move at about the same pace.
What is folic acid for when you are taking methotrexate?
Folic acid is commonly taken on the other days of the week. It tops up the folate that methotrexate blocks, which cuts down mouth ulcers, nausea and fatigue without cancelling the treatment's effect. It is a separate tablet from your methotrexate dose.
Does methotrexate cause hair loss?
Thinning hair is a known side effect, though it is usually mild and more noticeable at higher doses. Many people find it eases once the body adjusts or the weekly amount is lowered, and hair generally returns to normal after the medicine is stopped.
Can I take ibuprofen or other anti-inflammatory painkillers with methotrexate?
NSAIDs such as ibuprofen, naproxen and diclofenac slow the way the kidneys clear methotrexate, so levels in the blood can rise and side effects become more likely. The effect is strongest at higher weekly doses, and it applies to both prescription and over-the-counter versions.
About Methotrexate
What Methotrexate 2.5mg tablets are for
Methotrexate interferes with folate, the vitamin cells need to make new DNA, and the cells that divide fastest feel it most. In rheumatoid arthritis those are the overactive immune cells that keep joints inflamed. That puts it among the DMARDs (disease-modifying antirheumatic drugs), medicines that act on the disease itself instead of only dulling the pain.
It is used for rheumatoid arthritis, where the immune system attacks the joints and causes pain, swelling and stiffness; for psoriasis, the raised scaly patches on the skin; for psoriatic arthritis, where skin and joints are both affected; and for some cancers. The doses used for arthritis and psoriasis are far lower than those used in cancer treatment, which is why the 2.5mg tablet is the strength you see here.
How Methotrexate is taken
The schedule matters more than anything else with this medicine: one dose a week, on the same day each week. It is not a daily tablet. Swallow the tablets with water, and if a dose leaves you queasy, take it with a meal instead.
Side effects
Nausea, loss of appetite, mouth ulcers, loose stools and a washed-out feeling are the ones people notice most, and they often settle as the body gets used to the medicine. Headache and tiredness are reported as well.
Less commonly, methotrexate damages the liver, inflames the lungs or lowers the number of blood cells, which can show up as infections that linger, unusual bruising or bleeding, or breathlessness. Mouth ulcers that will not heal, a new dry cough, yellowing of the skin or eyes, or unexplained bruising need urgent attention. Regular blood tests check the liver, kidneys and blood counts during treatment.
Alcohol and other medicines
Alcohol and methotrexate both put strain on the liver, and drinking regularly while taking it makes liver damage more likely. Some medicines push the amount of methotrexate in the body higher, among them anti-inflammatory painkillers and certain antibiotics such as trimethoprim.
Ordering Methotrexate 2.5mg tablets
This listing is the 2.5mg tablet, sold in packs of 30, 60, 90 or 120. Keep the blister strips in the original box, in a cool place out of direct sunlight.
Sources
- Methotrexate: MedlinePlus Drug Information — National Library of Medicine
- Rheumatoid arthritis (RA) - symptoms, causes, complications and treatments - Healthdirect — Healthdirect Australia